Structure–activity relationship and in silico study of unique bi-heterocycles: 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazole-2-thiol derivatives
This paper presents the synthesis of some unique bi-heterocyclic hybrid molecules with a thiazole and an oxadiazole ring. The synthesis was initiated by the conversion of ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate (1) to the corresponding 2-(2-amino-1,3-thiazol-4-yl)acetohydrazide (2) by the reaction...
| Published in: | Journal of the Serbian Chemical Society |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Serbian Chemical Society
2019
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071284618&doi=10.2298%2fJSC180203019A&partnerID=40&md5=579ade91e32eb71c0f380e66e793bf5f |