A biosynthetic numbering system for diterpene pyrones
Diterpene pyrones, spiroditerpenoids, and brevianes are names given to a series of fungal meroterpenoids that share common structural features and a common biosynthetic pathway elaborated by multiple oxidations, rearrangements, and cyclizations to produce the observed structural diversity. A unifyin...
Published in: | Natural Product Communications |
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Format: | Review |
Language: | English |
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SAGE Publications Inc.
2019
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069749439&doi=10.1177%2f1934578X19860366&partnerID=40&md5=7ff10d0f8e11bc4e5ec41d232dc25b44 |
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2-s2.0-85069749439 Al-Khdhairawi A.A.Q.; Cordell G.A.; Weber J.F.; Nagojappa N.B.S. A biosynthetic numbering system for diterpene pyrones 2019 Natural Product Communications 14 7 10.1177/1934578X19860366 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069749439&doi=10.1177%2f1934578X19860366&partnerID=40&md5=7ff10d0f8e11bc4e5ec41d232dc25b44 Diterpene pyrones, spiroditerpenoids, and brevianes are names given to a series of fungal meroterpenoids that share common structural features and a common biosynthetic pathway elaborated by multiple oxidations, rearrangements, and cyclizations to produce the observed structural diversity. A unifying approach to the numbering of these fungal metabolites, based on a common biosynthetic progenitor, a geranylgeranyl-pyrone hybrid, is presented. This proposal will foster simplicity through a standardized numbering system that can be applied to the known members of this family, as well as to future metabolites. © The Author(s) 2019. SAGE Publications Inc. 1934578X English Review All Open Access; Hybrid Gold Open Access |
author |
Al-Khdhairawi A.A.Q.; Cordell G.A.; Weber J.F.; Nagojappa N.B.S. |
spellingShingle |
Al-Khdhairawi A.A.Q.; Cordell G.A.; Weber J.F.; Nagojappa N.B.S. A biosynthetic numbering system for diterpene pyrones |
author_facet |
Al-Khdhairawi A.A.Q.; Cordell G.A.; Weber J.F.; Nagojappa N.B.S. |
author_sort |
Al-Khdhairawi A.A.Q.; Cordell G.A.; Weber J.F.; Nagojappa N.B.S. |
title |
A biosynthetic numbering system for diterpene pyrones |
title_short |
A biosynthetic numbering system for diterpene pyrones |
title_full |
A biosynthetic numbering system for diterpene pyrones |
title_fullStr |
A biosynthetic numbering system for diterpene pyrones |
title_full_unstemmed |
A biosynthetic numbering system for diterpene pyrones |
title_sort |
A biosynthetic numbering system for diterpene pyrones |
publishDate |
2019 |
container_title |
Natural Product Communications |
container_volume |
14 |
container_issue |
7 |
doi_str_mv |
10.1177/1934578X19860366 |
url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069749439&doi=10.1177%2f1934578X19860366&partnerID=40&md5=7ff10d0f8e11bc4e5ec41d232dc25b44 |
description |
Diterpene pyrones, spiroditerpenoids, and brevianes are names given to a series of fungal meroterpenoids that share common structural features and a common biosynthetic pathway elaborated by multiple oxidations, rearrangements, and cyclizations to produce the observed structural diversity. A unifying approach to the numbering of these fungal metabolites, based on a common biosynthetic progenitor, a geranylgeranyl-pyrone hybrid, is presented. This proposal will foster simplicity through a standardized numbering system that can be applied to the known members of this family, as well as to future metabolites. © The Author(s) 2019. |
publisher |
SAGE Publications Inc. |
issn |
1934578X |
language |
English |
format |
Review |
accesstype |
All Open Access; Hybrid Gold Open Access |
record_format |
scopus |
collection |
Scopus |
_version_ |
1809677905773461504 |