A biosynthetic numbering system for diterpene pyrones
Diterpene pyrones, spiroditerpenoids, and brevianes are names given to a series of fungal meroterpenoids that share common structural features and a common biosynthetic pathway elaborated by multiple oxidations, rearrangements, and cyclizations to produce the observed structural diversity. A unifyin...
| Published in: | Natural Product Communications |
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| Main Author: | |
| Format: | Review |
| Language: | English |
| Published: |
SAGE Publications Inc.
2019
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069749439&doi=10.1177%2f1934578X19860366&partnerID=40&md5=7ff10d0f8e11bc4e5ec41d232dc25b44 |
| Summary: | Diterpene pyrones, spiroditerpenoids, and brevianes are names given to a series of fungal meroterpenoids that share common structural features and a common biosynthetic pathway elaborated by multiple oxidations, rearrangements, and cyclizations to produce the observed structural diversity. A unifying approach to the numbering of these fungal metabolites, based on a common biosynthetic progenitor, a geranylgeranyl-pyrone hybrid, is presented. This proposal will foster simplicity through a standardized numbering system that can be applied to the known members of this family, as well as to future metabolites. © The Author(s) 2019. |
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| ISSN: | 1934578X |
| DOI: | 10.1177/1934578X19860366 |