Conventional versus microwave assisted synthesis, molecular docking and enzyme inhibitory activities of new 3,4,5-trisubstituted-1,2,4-triazole analogues
N-(Substituted)-5-(1-(4-methoxyphenylsulfonyl)piperidin-4-yl)-4H-1,2,4-triazol-3-ylthio) acetamide were synthesized by following conventional as well as microwave assisted protocol through five consecutive steps under the impact of various reaction conditions to control the reaction time and the yie...
Published in: | Pakistan journal of pharmaceutical sciences |
---|---|
Main Author: | Virk N.A.; Rehman A.; Abbasi M.A.; Siddiqui S.Z.; Rashid U.; Iqbal J.; Saleem M.; Ashraf M.; Shahid W.; Shah S.A.A. |
Format: | Article |
Language: | English |
Published: |
NLM (Medline)
2018
|
Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064722727&partnerID=40&md5=0a69ac8f82ce083cf95b3c710152cca8 |
Similar Items
-
Novel 1,2,4-triazoles as anti-enzymatic agents: Microwave versus conventional synthesis, characterization, docking and BSA binding studies
by: Akhtar Virk N.; Rehman A.U.; Shuaib A.; Iqbal J.; Rasool S.; Al-Mijalli S.H.; Abid M.A.; Nisa M.-U.; Ali Shah S.A.; Saadiq M.
Published: (2023) -
Synthesis, enzyme inhibitory kinetics, & computational studies of N-(substituted phenyl)-(5-(3,4-dichlorobenzyl)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-ylthio)methylbenzamides: As potent alkaline phosphatase inhibitors
by: Zeb A.; Siddiqui S.Z.; Abbasi M.A.; Aziz-ur-Rehman; Shah S.A.A.; Imran S.; Raza H.; Kim S.J.; Parveen R.; Abbas G.
Published: (2025) -
Synthesis, enzyme inhibitory kinetics, & computational studies of N-(substituted phenyl)-(5-(3,4-dichlorobenzyl)-4-(4-chlorophenyl)-4H-1,2,4-triazol-3-ylthio)methylbenzamides: As potent alkaline phosphatase inhibitors
by: Zeb, et al.
Published: (2025) -
Discovery of Dual Inhibitors of Acetyl and Butrylcholinesterase and Antiproliferative Activity of 1,2,4-Triazole-3-thiol: Synthesis and In Silico Molecular Study
by: Siddiqui S.Z.; Arfan M.; Abbasi M.A.; Aziz-ur-Rehman; Shah S.A.A.; Ashraf M.; Hussain S.; Saleem R.S.Z.; Rafique R.; Khan K.M.
Published: (2020) -
In vitro and in silico assessment of bioactivity properties and pharmacokinetic studies of new 3,5-disubstituted-1,2,4-triazoles
by: Amjad H.; Abbasi M.A.; Siddiqui S.Z.; Iqbal J.; Rasool S.; Ashraf M.; Hussain S.; Shah S.A.A.; Imran S.; Shahid M.; Rasool A.; Rehman M.T.; Rehman A.U.
Published: (2023)