Synthesis and structure-activity relationship of tyrosinase inhibiting novel bi-heterocyclic acetamides: Mechanistic insights through enzyme inhibition, kinetics and computational studies

The present research was designed for the selective synthesis of novel bi-heterocyclic acetamides, 9a-n, and their tyrosinase inhibition to overwhelm the problem of melanogenesis. The structures of newly synthesized compounds were confirmed by spectral techniques such as...

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書目詳細資料
發表在:Bioorganic Chemistry
主要作者: Butt A.R.S.; Abbasi M.A.; Aziz-ur-Rehman; Siddiqui S.Z.; Raza H.; Hassan M.; Shah S.A.A.; Shahid M.; Seo S.-Y.
格式: Article
語言:English
出版: Academic Press Inc. 2019
在線閱讀:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061452076&doi=10.1016%2fj.bioorg.2019.01.036&partnerID=40&md5=6014762675de57ae6db479fe795c8cfe