Domperidone nanocrystals with boosted oral bioavailability: fabrication, evaluation and molecular insight into the polymer-domperidone nanocrystal interaction

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Domperidone nanocrystals with boosted oral bioavailability: fabrication, evaluation and molecular insight into the polymer-domperidone nanocrystal interaction

The aim of this study was to employ experimental and molecular modelling approaches to use molecular level interactions to rationalise the selection of suitable polymers for use in the production of stable domperidone (DOMP) nanocrystals with enhanced bioavailability. A low-energy antisolvent precip...

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Bibliographic Details
Published in:	Drug Delivery and Translational Research
Main Author:	Ndlovu S.T.; Ullah N.; Khan S.; Ramharack P.; Soliman M.; de Matas M.; Shahid M.; Sohail M.; Imran M.; Shah S.W.A.; Hussain Z.
Format:	Article
Language:	English
Published:	Springer Verlag 2019
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059829630&doi=10.1007%2fs13346-018-00596-w&partnerID=40&md5=87bd281b490efeb6588739abc50ef57c

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