Bi-heterocyclic benzamides as alkaline phosphatase inhibitors: Mechanistic comprehensions through kinetics and computational approaches

Novel bi-heterocyclic benzamides were synthesized by sequentially converting 4-(1H-indol-3-yl)butanoic acid (1) into ethyl 4-(1H-indol-3-yl)butanoate (2), 4-(1H-indol-3-yl)butanohydrazide (3), and a nucleophilic 5-[3-(1H-indol-3-yl)propyl]-1,3,4-oxadiazole-2-thiol (4). I...

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Bibliographic Details
Published in:Archiv der Pharmazie
Main Author: Abbasi M.A.; Nazir M.; ur-Rehman A.; Siddiqui S.Z.; Hassan M.; Raza H.; Shah S.A.A.; Shahid M.; Seo S.-Y.
Format: Article
Language:English
Published: Wiley-VCH Verlag 2019
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059670968&doi=10.1002%2fardp.201800278&partnerID=40&md5=5b8723c8342b1711229fed475f428094

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