Smart combination of β-cyclodextrin polymer-conjugated magnetic nanosorbent for potential adsorption of deoxyribonucleic acid

• Published in: Separation Science and Technology (Philadelphia)
• Main Author: Ying Hwa G.; Yih Hui B.; Jairaj Moses E.; Shahriman M.S.; Md Yusoff M.; Yahaya N.; Sambasevam K.P.; Surikumaran H.; Chandrasekaram K.; Raoov M.
• Format: Article
• Language: English
• Published: Taylor and Francis Inc. 2019
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054355462&doi=10.1080%2f01496395.2018.1524485&partnerID=40&md5=28a445b5dcd40475c6ef76b71f617e95

We reported the synthesis and characterization of Fe 3 O 4 magnetic nanoparticles modified β-cyclodextrin polymer (MNP@βCD-TDI) for the adsorption of deoxyribonucleic acid (DNA). The synthesized MNP@βCD-TDI was characterized by Fourier Transform Infra-Red spectroscopy and Vibrating Sample Magnetometer. Experiments were performed in a batch mode and parameters that affected the DNA adsorption were investigated. An evaluation of the adsorption behavior revealed that Freundlich model and pseudo-second-order fit the equilibrium data. The adsorption efficiency of DNA was found to be at 70 ± 5 % after being recycled three times. This study could be used as a general platform for future work on DNA adsorption and enrichment. © 2018, © 2018 Taylor & Francis.