Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects

Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects

Hyaluronic acid (HA) plays multifaceted role in regulating the various biological processes such as skin repairmen, diagnosis of cancer, wound healing, tissue regeneration, anti-inflammatory, and immunomodulation. Owing to its remarkable biomedical and tissue regeneration potential, HA has been nume...

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Bibliographic Details
Published in:International Journal of Biological Macromolecules
Main Author: Bukhari S.N.A.; Roswandi N.L.; Waqas M.; Habib H.; Hussain F.; Khan S.; Sohail M.; Ramli N.A.; Thu H.E.; Hussain Z.
Format: Review
Language:English
Published: Elsevier B.V. 2018
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054310996&doi=10.1016%2fj.ijbiomac.2018.09.188&partnerID=40&md5=ad5d784248b17e35c74699bca5d19a5d
id 2-s2.0-85054310996
spelling 2-s2.0-85054310996
Bukhari S.N.A.; Roswandi N.L.; Waqas M.; Habib H.; Hussain F.; Khan S.; Sohail M.; Ramli N.A.; Thu H.E.; Hussain Z.
Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
2018
International Journal of Biological Macromolecules
120

10.1016/j.ijbiomac.2018.09.188
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054310996&doi=10.1016%2fj.ijbiomac.2018.09.188&partnerID=40&md5=ad5d784248b17e35c74699bca5d19a5d
Hyaluronic acid (HA) plays multifaceted role in regulating the various biological processes such as skin repairmen, diagnosis of cancer, wound healing, tissue regeneration, anti-inflammatory, and immunomodulation. Owing to its remarkable biomedical and tissue regeneration potential, HA has been numerously employed as one of the imperative components of the cosmetic and nutricosmetic products. The present review aims to summarize and critically appraise recent developments and clinical investigations on cosmetic and nutricosmetic efficacy of HA for skin rejuvenation. A thorough analysis of the literature revealed that HA based formulations (i.e., gels, creams, intra-dermal filler injections, dermal fillers, facial fillers, autologous fat gels, lotion, serum, and implants, etc.) exhibit remarkable anti-wrinkle, anti-nasolabial fold, anti-aging, space-filling, and face rejuvenating properties. This has been achieved via soft tissue augmentation, improved skin hydration, collagen and elastin stimulation, and face volume restoration. HA, alone or in combination with lidocaine and other co-agents, showed promising efficacy in skin tightness and elasticity, face rejuvenation, improving aesthetic scores, reducing the wrinkle scars, longevity, and tear trough rejuvenation. Our critical analysis evidenced that application/administration of HA exhibits outstanding nutricosmetic efficacy and thus is warranted to be used as a prime component of cosmetic products. © 2018
Elsevier B.V.
1418130
English
Review
author Bukhari S.N.A.; Roswandi N.L.; Waqas M.; Habib H.; Hussain F.; Khan S.; Sohail M.; Ramli N.A.; Thu H.E.; Hussain Z.
spellingShingle Bukhari S.N.A.; Roswandi N.L.; Waqas M.; Habib H.; Hussain F.; Khan S.; Sohail M.; Ramli N.A.; Thu H.E.; Hussain Z.
Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
author_facet Bukhari S.N.A.; Roswandi N.L.; Waqas M.; Habib H.; Hussain F.; Khan S.; Sohail M.; Ramli N.A.; Thu H.E.; Hussain Z.
author_sort Bukhari S.N.A.; Roswandi N.L.; Waqas M.; Habib H.; Hussain F.; Khan S.; Sohail M.; Ramli N.A.; Thu H.E.; Hussain Z.
title Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
title_short Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
title_full Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
title_fullStr Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
title_full_unstemmed Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
title_sort Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects
publishDate 2018
container_title International Journal of Biological Macromolecules
container_volume 120
container_issue
doi_str_mv 10.1016/j.ijbiomac.2018.09.188
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054310996&doi=10.1016%2fj.ijbiomac.2018.09.188&partnerID=40&md5=ad5d784248b17e35c74699bca5d19a5d
description Hyaluronic acid (HA) plays multifaceted role in regulating the various biological processes such as skin repairmen, diagnosis of cancer, wound healing, tissue regeneration, anti-inflammatory, and immunomodulation. Owing to its remarkable biomedical and tissue regeneration potential, HA has been numerously employed as one of the imperative components of the cosmetic and nutricosmetic products. The present review aims to summarize and critically appraise recent developments and clinical investigations on cosmetic and nutricosmetic efficacy of HA for skin rejuvenation. A thorough analysis of the literature revealed that HA based formulations (i.e., gels, creams, intra-dermal filler injections, dermal fillers, facial fillers, autologous fat gels, lotion, serum, and implants, etc.) exhibit remarkable anti-wrinkle, anti-nasolabial fold, anti-aging, space-filling, and face rejuvenating properties. This has been achieved via soft tissue augmentation, improved skin hydration, collagen and elastin stimulation, and face volume restoration. HA, alone or in combination with lidocaine and other co-agents, showed promising efficacy in skin tightness and elasticity, face rejuvenation, improving aesthetic scores, reducing the wrinkle scars, longevity, and tear trough rejuvenation. Our critical analysis evidenced that application/administration of HA exhibits outstanding nutricosmetic efficacy and thus is warranted to be used as a prime component of cosmetic products. © 2018
publisher Elsevier B.V.
issn 1418130
language English
format Review
accesstype
record_format scopus
collection Scopus
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