Polymer-wrapped single-walled carbon nanotubes: a transformation toward better applications in healthcare

• Published in: Drug Delivery and Translational Research
• Main Author: Chik M.W.; Hussain Z.; Zulkefeli M.; Tripathy M.; Kumar S.; Majeed A.B.A.; Byrappa K.
• Format: Review
• Language: English
• Published: Springer Verlag 2019
• Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054098944&doi=10.1007%2fs13346-018-0505-9&partnerID=40&md5=18a5ee4a6fe6a5f9d2f6b541cf79a23d

Carbon nanotubes (CNTs) possess outstanding properties that could be useful in several technological, drug delivery, and diagnostic applications. However, their unique physical and chemical properties are hindered due to their poor solubility. This article review’s the different ways and means of solubility enhancement of single-wall carbon nanotubes (SWNTs). The advantages of SWNTs over the multi-walled carbon nanotubes (MWNTs) and the method of non-covalent modification for solubility enhancement has been the key interest in this review. The review also highlights a few examples of dispersant design. The review includes some interesting utility of SWNTs being wrapped with polymer especially in biological media that could mediate proper drug delivery to target cells. Further, the use of wrapped SWNTs with phospholipids, nucleic acid, and amphiphillic polymers as biosensors is of research interest. The review aims at summarizing the developments relating to wrapped SWNTs to generate further research prospects in healthcare. © 2018, Controlled Release Society.