Pyrimidine derivatives of n-acetylguanidine: Novel inhibitors of sodium-hydrogen exchanger 1

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Pyrimidine derivatives of n-acetylguanidine: Novel inhibitors of sodium-hydrogen exchanger 1

Sodium-hydrogen exchanger (Na+/H+) type 1 (NHE-1) inhibitors have been shown to protect the heart during ischaemia and early reperfusion. As such, NHE-1 inhibitors are of special interest for clinical development for the attenuation of both acute and chronic post-myocardial infarction responses. New...

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Bibliographic Details
Published in:	Heterocycles
Main Author:	Ozerov A.; Novikov M.; Spasov A.; Iezhitsa I.; Gurova N.; Gurova V.
Format:	Article
Language:	English
Published:	Japan Institute of Heterocyclic Chemistry 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051959874&doi=10.3987%2fCOM-18-13904&partnerID=40&md5=39d4a0b4c03d631d58a84861bd84e99f

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