Pyrimidine derivatives of n-acetylguanidine: Novel inhibitors of sodium-hydrogen exchanger 1
Sodium-hydrogen exchanger (Na+/H+) type 1 (NHE-1) inhibitors have been shown to protect the heart during ischaemia and early reperfusion. As such, NHE-1 inhibitors are of special interest for clinical development for the attenuation of both acute and chronic post-myocardial infarction responses. New...
| Published in: | Heterocycles |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Japan Institute of Heterocyclic Chemistry
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051959874&doi=10.3987%2fCOM-18-13904&partnerID=40&md5=39d4a0b4c03d631d58a84861bd84e99f |