Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs

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Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs

α-Glucosidase is a catabolic enzyme that regulates the body's plasma glucose levels by providing energy sources to maintain healthy functioning. 2-Amino-thiadiazole (1–13) and 2-amino-thiadiazole based Schiff bases (14–22) were synthesized, characterized by 1H NMR and HREI-MS and screened for α...

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Bibliographic Details
Published in:	Bioorganic Chemistry
Main Author:	Javid M.T.; Rahim F.; Taha M.; Rehman H.U.; Nawaz M.; wadood A.; Imran S.; Uddin I.; Mosaddik A.; Khan K.M.
Format:	Article
Language:	English
Published:	Academic Press Inc. 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044438335&doi=10.1016%2fj.bioorg.2018.03.022&partnerID=40&md5=a6ede95c89d954b150d814bae0bde0db

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