Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs
α-Glucosidase is a catabolic enzyme that regulates the body's plasma glucose levels by providing energy sources to maintain healthy functioning. 2-Amino-thiadiazole (1–13) and 2-amino-thiadiazole based Schiff bases (14–22) were synthesized, characterized by 1H NMR and HREI-MS and screened for α...
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85044438335&doi=10.1016%2fj.bioorg.2018.03.022&partnerID=40&md5=a6ede95c89d954b150d814bae0bde0db |