Synthesis, molecular docking study and thymidine phosphorylase inhibitory activity of 3-formylcoumarin derivatives

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Synthesis, molecular docking study and thymidine phosphorylase inhibitory activity of 3-formylcoumarin derivatives

Thymidine phosphorylase (TP) over expression plays role in several pathological conditions, such as rheumatoid arthritis, chronic inflammatory diseases, psoriasis, and tumor angiogenesis. The inhibitor of this enzyme plays an important role in preventing the serious threat due to over expression of...

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Bibliographic Details
Published in:	Bioorganic Chemistry
Main Author:	Taha M.; Adnan Ali Shah S.; Afifi M.; Imran S.; Sultan S.; Rahim F.; Hadiani Ismail N.; Mohammed Khan K.
Format:	Article
Language:	English
Published:	Academic Press Inc. 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042907693&doi=10.1016%2fj.bioorg.2018.02.028&partnerID=40&md5=9b94f4076ef61fbd0fc443e4ff380a96

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