Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats

QR Code

Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats

Background: Melastoma malabathricum L. (family Melastomaceae; MM) and Muntingia calabura L. (family Elaeocarpaceae; MC) have been separately reported to possess gastroprotective activity. In an attempt to develop a pharmaceutical product with antiulcer potential, the synergistic gastroprotective act...

Full description

Bibliographic Details
Published in:	BMC Complementary and Alternative Medicine
Main Author:	Halim S.Z.; Zakaria Z.A.; Omar M.H.; Mohtarrudin N.; Wahab I.R.A.; Abdullah M.N.H.
Format:	Article
Language:	English
Published:	BioMed Central Ltd. 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033775397&doi=10.1186%2fs12906-017-1992-9&partnerID=40&md5=994651023b324a6393d0b1f4b4ac8976

Similar Items

Mechanisms of gastroprotection of methanol extract of Melastoma malabathricum leaves
by: Zakaria Z.A.; Balan T.; Mamat S.S.; Mohtarrudin N.; Kek T.L.; Salleh M.Z.
Published: (2015)

Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura
by: Zakaria Z.A.; Balan T.; Azemi A.K.; Omar M.H.; Mohtarrudin N.; Ahmad Z.; Abdullah M.N.H.; Desa M.N.M.; Teh L.K.; Salleh M.Z.
Published: (2016)

Amelioration of paracetamol-induced hepatotoxicity in rat by the administration of methanol extract of Muntingia calabura L. Leaves
by: Mahmood N.D.; Mamat S.S.; Kamisan F.H.; Yahya F.; Kamarolzaman M.F.F.; Nasir N.; Mohtarrudin N.; Tohid S.F.M.; Zakaria Z.A.
Published: (2014)

Semipurified Ethyl Acetate Partition of Methanolic Extract of Melastoma malabathricum Leaves Exerts Gastroprotective Activity Partly via Its Antioxidant-Antisecretory-Anti-Inflammatory Action and Synergistic Action of Several Flavonoid-Based Compounds
by: Ismail Suhaimy N.W.; Noor Azmi A.K.; Mohtarrudin N.; Omar M.H.; Tohid S.F.M.; Cheema M.S.; Teh L.K.; Salleh M.Z.; Zakaria Z.A.
Published: (2017)

Possible mechanisms of antinociception of methanol extract of Melastoma malabathricum leaves
by: Jaios E.S.; Rahman S.; Ching S.M.; Kadir A.A.; Desa M.N.M.; Zakaria Z.A.
Published: (2016)

Antinociceptive activity of methanolic extract of Muntingia calabura leaves: Further elucidation of the possible mechanisms
by: Zakaria Z.A.; Sani M.H.M.; Cheema M.S.; Kader A.A.; Kek T.L.; Salleh M.Z.
Published: (2014)

Methanol extract of Muntingia calabura leaves attenuates CCl4-induced liver injury: possible synergistic action of flavonoids and volatile bioactive compounds on endogenous defence system
by: Zakaria Z.A.; Mahmood N.D.; Omar M.H.; Taher M.; Basir R.
Published: (2019)

Antinociception of petroleum ether fraction derived from crude methanol extract of Melastoma malabathricum leaves and its possible mechanisms of action in animal models
by: Zakaria Z.A.; Jaios E.S.; Omar M.H.; Abd. Rahman S.; Hamid S.S.A.; Ching S.M.; Teh L.K.; Salleh M.Z.; Deny S.; Taher M.
Published: (2016)

Melastoma malabathricum (L.) smith ethnomedicinal uses, chemical constituents, and pharmacological properties: A review
by: Joffry S.M.; Yob N.J.; Rofiee M.S.; Affandi M.M.R.M.M.; Suhaili Z.; Othman F.; Akim A.M.; Desa M.N.M.; Zakaria Z.A.
Published: (2012)

Hepatoprotective activity of methanolic extract of bauhinia purpurea leaves against paracetamol-induced hepatic damage in rats
by: Yahya F.; Mamat S.S.; Kamarolzaman M.F.F.; Seyedan A.A.; Jakius K.F.; Mahmood N.D.; Shahril M.S.; Suhaili Z.; Mohtarrudin N.; Susanti D.; Somchit M.N.; Teh L.K.; Salleh M.Z.; Zakaria Z.A.
Published: (2013)

Effects of palm kernel biochar on the physiological responses and root profiles of sendudok (Melastoma malabathricum l.) grown on acidic soil
by: Rusli L.S.; Osman N.; Abdullah R.; Yaacob J.S.; Seow A.H.
Published: (2021)

Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride- induced acute liver injury in rats
by: Kamisan F.H.; Yahya F.; Mamat S.S.; Kamarolzaman M.F.F.; Mohtarrudin N.; Kek T.L.; Salleh M.Z.; Hussain M.K.; Zakaria Z.A.
Published: (2014)

Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: Involvement of the antioxidant mechanisms
by: Zakaria Z.A.; Yahya F.; Mamat S.S.; Mahmood N.D.; Mohtarrudin N.; Taher M.; Hamid S.S.A.; Teh L.K.; Salleh M.Z.
Published: (2016)

Gastroprotective effects of Corchorus olitorius leaf extract against ethanol-induced gastric mucosal hemorrhagic lesions in rats
by: Al Batran R.; Al-Bayaty F.; Ameen Abdulla M.; Jamil Al-Obaidi M.M.; Hajrezaei M.; Hassandarvish P.; Fouad M.; Golbabapour S.; Talaee S.
Published: (2013)

Polyphenolics and triterpenes presence in chloroform extract of Dicranopteris linearis leaves attenuated paracetamol-induced liver intoxication in rat
by: Zakaria Z.A.; Sahmat A.; Azmi A.H.; Nur Zainol A.S.; Omar M.H.; Balan T.; Sulistyorini L.; Azizah R.; Abdullah M.N.H.
Published: (2021)

Antinociceptive Activity of Methanolic Extract of Clinacanthus nutans Leaves: Possible Mechanisms of Action Involved
by: Zakaria Z.A.; Abdul Rahim M.H.; Roosli R.A.J.; Mohd Sani M.H.; Omar M.H.; Tohid S.F.; Othman F.; Ching S.M.; Abdul Kadir A.
Published: (2018)

Analysis of bioactive compounds from the leaves part of Melastoma malabatrichum, Clidemia hirta, Chromolaena odorata, and Ageratum conyzoides by gas chromatography-mass spectrometry
by: Ismail N.H.; Hamid N.A.; Zain W.Z.W.M.; Latip S.N.H.M.; Hamzah F.; Aani S.N.A.
Published: (2022)

Methanol extract of Dicranopteris linearis leaves attenuate pain via the modulation of opioid/NO-mediated pathway
by: Zakaria Z.A.; Roosli R.A.J.; Marmaya N.H.; Omar M.H.; Basir R.; Somchit M.N.
Published: (2020)

Acute and sub-chronic oral toxicity studies of methanol extract of clinacanthus nutans in mice
by: Zakaria Z.A.; Rahim M.H.A.; Mohtarrudin N.; Kadir A.A.; Cheema M.S.; Ahmad Z.; Mooi C.S.; Tohid S.F.M.
Published: (2016)

Article methanolic extract of piper sarmentosum attenuates obesity and hyperlipidemia in fructose-induced metabolic syndrome rats
by: Kumar S.R.; Ramli E.S.M.; Nasir N.A.A.; Ismail N.M.; Fahami N.A.M.
Published: (2021)

Synergistic hepatoprotective potential of ethanolic extract of Solanum xanthocarpum and Juniperus communis against paracetamol and azithromycin induced liver injury in rats
by: Singh H.; Prakash A.; Kalia A.N.; Majeed A.B.A.
Published: (2016)

The osteoprotective effect of azadirachta excelsa leaves extract on bone of streptozotocin-induced diabetic rats
by: Azmi N.S.; Hashim N.; Samsulrizal N.; Zin N.S.N.M.
Published: (2019)

Potential antidiabetic activity of Plantago Major leaves extract in Streptozocin-induced diabetic rats
by: Abdulghani M.A.; Hamid I.; Al-Naggar R.A.; Osman M.T.
Published: (2014)

Antinociceptive Activity of Petroleum Ether Fraction of Clinacanthus nutans Leaves Methanolic Extract: Roles of Nonopioid Pain Modulatory Systems and Potassium Channels
by: Zakaria Z.A.; Abdul Rahim M.H.; Roosli R.A.J.; Mohd Sani M.H.; Marmaya N.H.; Omar M.H.; Teh L.K.; Salleh M.Z.
Published: (2019)

Corrigendum: Gastroprotective activity of polygonum chinense aqueous leaf extract on ethanol-induced hemorrhagic mucosal lesions in rats (Evidence-Based Complementary and Alternative Medicine (2012) (404012) DOI: 10.1155/2012/404012)
by: Ismail I.F.; Golbabapour S.; Hassandarvish P.; Hajrezaie M.; Abdul Majid N.; Kadir F.A.; Al-Bayaty F.; Awang K.; Hazni H.; Abdulla M.A.
Published: (2018)

Rheological behavior of Zirconia Added alumina mixture
by: Aziz S.N.A.; Saidi W.S.S.W.; Bakar M.A.A.; Ismail M.H.
Published: (2018)

Sea cucumber (Stichopus hermanii) based hydrogel to treat burn wounds in rats
by: Zohdi R.M.; Zakaria Z.A.B.; Yusof N.; Mustapha N.M.; Abdullah M.N.H.
Published: (2011)

The methanolic extract of garcinia atroviridis (Mega) reduces body weight and food intake, and improves lipid profiles by altering the lipid metabolism: A rat model
by: Lim W.F.; Nasir S.M.; Teh L.K.; James R.J.; Izhar M.H.M.; Salleh M.Z.
Published: (2020)

Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway
by: Zakaria Z.A.; Abdul Rahim M.H.; Mohd Sani M.H.; Omar M.H.; Ching S.M.; Abdul Kadir A.; Ahmed Q.U.
Published: (2019)

Interactive mixture as a rapid drug delivery system
by: Lee C.C.; Ong C.L.C.; Heng P.W.S.; Chan L.W.; Wong T.W.
Published: (2008)

The Influence of Coal Bottom Ash as Filler in Asphalt Mixture
by: Ing N.L.S.; Ming N.C.; Hasan M.; Jaya R.P.; Shaffie E.; Mashros N.; Mohamed A.A.
Published: (2022)

Effects of Standardized Aqueous Ethanolic Extract of Leaves of Ficus Deltoidea var. Trengganuensis on Blood Pressure in Spontaneously Hypertensive Rats
by: Radjeni Z.; Aziz M.A.; Azis N.A.; Kamal M.S.A.; Singh H.J.
Published: (2024)

Methanol permeability enhancement through heat treatment of Nafion-based composite membrane for direct methanol fuel cell application
by: Elham O.S.J.; Kamarudin S.K.; Shaari N.; Zainoodin A.M.; Yusof M.R.
Published: (2024)

Phytochemical Screening, Antioxidant and Antifungal Activity of Methanolic Extract of Fimbristylis dichotoma and Fimbristylis miliacea
by: Ramli N.W.; Zain W.Z.W.M.; Wahab M.Z.A.; Hamid N.; Abdullah N.A.; Zamanhuri N.
Published: (2022)

Synergistic influence of neodymium oxide on optical nonlinearity of zinctellurite glass
by: Azlan M.N.; Azlina Y.; Shaari H.R.; Hisam R.; Al-Hada N.M.; Umar S.A.; Kenzhaliyev B.K.
Published: (2024)

Permeability coefficient of porous asphalt mixture containing coconut shells and fibres
by: Norhidayah A.H.; Haryati Y.; Nordiana M.; Khairul Idham M.S.M.; Juraidah A.; Ramadhansyah P.J.
Published: (2019)

Analysis of Algae and Bacteria Mixture in Removing Pollutants from Laundry Wastewater
by: Rodzi N.A.A.M.; Kasmuri N.; Zaini N.; Azri N.A.A.; Nayono S.E.
Published: (2024)

Ammonia-nitrogen and phosphate removal in leachate using algae and bacteria mixture
by: Kasmuri N.; Misni M.Z.
Published: (2019)

Evaluation of phytoactive contents and antibacterial activities of green synthesised cerium oxide nanoparticles using Melastoma sp. leaf extract as the capping agent
by: Hasan, et al.
Published: (2024)

Evaluation of phytoactive contents and antibacterial activities of green synthesised cerium oxide nanoparticles using Melastoma sp. leaf extract as the capping agent
by: Hasan N.A.; Wazir N.N.; Samsudin M.Y.; Syahmi Mohd Sanizam M.M.; Ahmad N.M.; Badrol Hisham N.A.; Yasin Y.; Nik Masdek N.R.
Published: (2024)