Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species

In this paper, we investigate the potency of Leea indica locally known as Memali plant from Tasik Chini, Pahang as a potent antioxidant and antimicrobial agent. Antibacterial activity of root, stem and leaf extracts of L. indica was evaluated against skin disease caused-microb Staphylococcus aureus...

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Published in:Malaysian Journal of Science
Main Author: Harun A.; Rahim N.E.A.A.; Jalil M.A.A.; Rosdi N.A.M.; Daud S.; Harith S.S.; So'ad S.Z.M.; Hassan N.M.
Format: Article
Language:English
Published: Malaysian Abstracting and Indexing System 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033569883&doi=10.22452%2fmjs.vol35no2.12&partnerID=40&md5=30dd8dac966cfa656e56be37ed27de0a
id 2-s2.0-85033569883
spelling 2-s2.0-85033569883
Harun A.; Rahim N.E.A.A.; Jalil M.A.A.; Rosdi N.A.M.; Daud S.; Harith S.S.; So'ad S.Z.M.; Hassan N.M.
Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
2016
Malaysian Journal of Science
35
2
10.22452/mjs.vol35no2.12
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033569883&doi=10.22452%2fmjs.vol35no2.12&partnerID=40&md5=30dd8dac966cfa656e56be37ed27de0a
In this paper, we investigate the potency of Leea indica locally known as Memali plant from Tasik Chini, Pahang as a potent antioxidant and antimicrobial agent. Antibacterial activity of root, stem and leaf extracts of L. indica was evaluated against skin disease caused-microb Staphylococcus aureus and Staphylococcus epidermidis. Antioxidant activity was assessed by 2, 2 diphenyl-1-picrylhydrazyl ( DPPH) thin layer chromatography (TLC) and dot blot assay method. The dichloromethane (DCM) extracts of all three parts displayed obvious antibacterial effect compared to other extracts and DCM extracts from leaves was the most effective in inhibiting the growth of S. epidermis with inhibition zone (IZ) of 18 mm. The methanol extracts from stem scavenged DPPH radicals more effective than root and leaf extracts at a concentration as low as 0.19 mg/ml. The antibacterial and antioxidant properties of leaves and stem might be attributed to the high content of terpenoid and phenolic. Thus, Memali appears to be a promising source of bioactive ingredients with antioxidant and antimicrobial activity.
Malaysian Abstracting and Indexing System
13943065
English
Article
All Open Access; Bronze Open Access
author Harun A.; Rahim N.E.A.A.; Jalil M.A.A.; Rosdi N.A.M.; Daud S.; Harith S.S.; So'ad S.Z.M.; Hassan N.M.
spellingShingle Harun A.; Rahim N.E.A.A.; Jalil M.A.A.; Rosdi N.A.M.; Daud S.; Harith S.S.; So'ad S.Z.M.; Hassan N.M.
Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
author_facet Harun A.; Rahim N.E.A.A.; Jalil M.A.A.; Rosdi N.A.M.; Daud S.; Harith S.S.; So'ad S.Z.M.; Hassan N.M.
author_sort Harun A.; Rahim N.E.A.A.; Jalil M.A.A.; Rosdi N.A.M.; Daud S.; Harith S.S.; So'ad S.Z.M.; Hassan N.M.
title Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
title_short Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
title_full Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
title_fullStr Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
title_full_unstemmed Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
title_sort Comparative study of antioxidant and antimicrobial activity of root, stem and leaves of leea indica species
publishDate 2016
container_title Malaysian Journal of Science
container_volume 35
container_issue 2
doi_str_mv 10.22452/mjs.vol35no2.12
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033569883&doi=10.22452%2fmjs.vol35no2.12&partnerID=40&md5=30dd8dac966cfa656e56be37ed27de0a
description In this paper, we investigate the potency of Leea indica locally known as Memali plant from Tasik Chini, Pahang as a potent antioxidant and antimicrobial agent. Antibacterial activity of root, stem and leaf extracts of L. indica was evaluated against skin disease caused-microb Staphylococcus aureus and Staphylococcus epidermidis. Antioxidant activity was assessed by 2, 2 diphenyl-1-picrylhydrazyl ( DPPH) thin layer chromatography (TLC) and dot blot assay method. The dichloromethane (DCM) extracts of all three parts displayed obvious antibacterial effect compared to other extracts and DCM extracts from leaves was the most effective in inhibiting the growth of S. epidermis with inhibition zone (IZ) of 18 mm. The methanol extracts from stem scavenged DPPH radicals more effective than root and leaf extracts at a concentration as low as 0.19 mg/ml. The antibacterial and antioxidant properties of leaves and stem might be attributed to the high content of terpenoid and phenolic. Thus, Memali appears to be a promising source of bioactive ingredients with antioxidant and antimicrobial activity.
publisher Malaysian Abstracting and Indexing System
issn 13943065
language English
format Article
accesstype All Open Access; Bronze Open Access
record_format scopus
collection Scopus
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