Ursodeoxycholic acid protects cardiomyocytes against cobalt chloride induced hypoxia by regulating transcriptional mediator of cells stress hypoxia inducible factor 1α and p53 protein
In hepatocytes, ursodeoxycholic acid (UDCA) activates cell signalling pathways such as p53, intracellular calcium ([Ca2+]i), and sphingosine-1-phosphate (S1P)-receptor via Gαi-coupled-receptor. Recently, UDCA has been shown to protect the heart against hypoxia-reoxygenation injury. However, it is no...
| 发表在: | Cell Biochemistry and Function |
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| 主要作者: | |
| 格式: | 文件 |
| 语言: | English |
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John Wiley and Sons Ltd
2017
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| 在线阅读: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85031325768&doi=10.1002%2fcbf.3303&partnerID=40&md5=76edac7ed2f6e599351797d27545b12b |