Synthesis and in vitro study of benzofuran hydrazone derivatives as novel alpha-amylase inhibitor

The α-amylase acts as attractive target to treat type-2 diabetes mellitus. Therefore in discovering a small molecule as α-amylase inhibitor, we have synthesized benzofuran carbohydrazide analogs (1–25), characterized through different spectroscopic techniques such as 1HNMR and EI-MS. All screened an...

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Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Taha M.; Shah S.A.A.; Imran S.; Afifi M.; Chigurupati S.; Selvaraj M.; Rahim F.; Ullah H.; Zaman K.; Vijayabalan S.
Format: Article
Language:English
Published: Academic Press Inc. 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029439458&doi=10.1016%2fj.bioorg.2017.09.002&partnerID=40&md5=e155d24e0825cff3a5615c54fd70e6e6

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