Aceclofenac nanocrystals with enhanced in vitro, in vivo performance: Formulation optimization, characterization, analgesic and acute toxicity studies

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Aceclofenac nanocrystals with enhanced in vitro, in vivo performance: Formulation optimization, characterization, analgesic and acute toxicity studies

This study was aimed to enhance the dissolution rate, oral bioavailability and analgesic potential of the aceclofenac (AC) in the form of nanosuspension using cost-effective simple precipitation–ultrasonication approach. The nanocrystals were produced using the optimum conditions investigated for AC...

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Bibliographic Details
Published in:	Drug Design, Development and Therapy
Main Author:	Rahim H.; Sadiq A.; Khan S.; Khan M.A.; Shah S.M.H.; Hussain Z.; Ullah R.; Shahat A.A.; Ibrahim K.
Format:	Article
Language:	English
Published:	Dove Medical Press Ltd. 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028647685&doi=10.2147%2fDDDT.S140626&partnerID=40&md5=a63bf74942ce3b46edf3dd86044aec31

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