2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity

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2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity

Pyridyl-benzimidazole analogues 1-11 with variable substituent on phenyl ring of phenacyl moiety were synthesized and evaluated for their urease inhibitory activity. The compounds exhibited urease inhibition with IC50 between 19.22 and 77.31 μM. Compounds 4 (IC50 = 19.22 ± 0.49 μM) showed a urease i...

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Bibliographic Details
Published in:	Medicinal Chemistry Research
Main Author:	Saify Z.S.; Kamil A.; Akhtar S.; Taha M.; Khan A.; Khan K.M.; Jahan S.; Rahim F.; Perveen S.; Choudhary M.I.
Format:	Article
Language:	English
Published:	Birkhauser Boston 2014
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85027926278&doi=10.1007%2fs00044-014-1015-z&partnerID=40&md5=f027f7827a6f2f83909d4abaca7b6184

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