Synthesis and biological evaluation of indole derivatives as α-amylase inhibitor

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Synthesis and biological evaluation of indole derivatives as α-amylase inhibitor

A series of twenty indole hydrazone analogs (1–21) were synthesized, characterized by different spectroscopic techniques such as 1H NMR and EI-MS, and screened for α-amylase inhibitory activity. All analogs showed a variable degree of α-amylase inhibition with IC50 values ranging between 1.66 and 2....

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Bibliographic Details
Published in:	Bioorganic Chemistry
Main Author:	Imran S.; Taha M.; Selvaraj M.; Ismail N.H.; Chigurupati S.; Mohammad J.I.
Format:	Article
Language:	English
Published:	Academic Press Inc. 2017
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021060841&doi=10.1016%2fj.bioorg.2017.06.007&partnerID=40&md5=d9e7c98d5a0decd20b6a24143a22fabd

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