Synthesis and biological evaluation of indole derivatives as α-amylase inhibitor
A series of twenty indole hydrazone analogs (1–21) were synthesized, characterized by different spectroscopic techniques such as 1H NMR and EI-MS, and screened for α-amylase inhibitory activity. All analogs showed a variable degree of α-amylase inhibition with IC50 values ranging between 1.66 and 2....
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2017
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021060841&doi=10.1016%2fj.bioorg.2017.06.007&partnerID=40&md5=d9e7c98d5a0decd20b6a24143a22fabd |