Adverse effects of leptin on histone-to-protamine transition during spermatogenesis are prevented by melatonin in Sprague-Dawley rats

QR Code

Adverse effects of leptin on histone-to-protamine transition during spermatogenesis are prevented by melatonin in Sprague-Dawley rats

This study examines the effect of melatonin on leptin-induced changes in transition of histone to protamine in adult rats during spermatogenesis. Twelve-week-old Sprague-Dawley rats were randomised into control, leptin-, leptin–melatonin-10-, leptin–melatonin-20- and melatonin-10-treated groups with...

Full description

Bibliographic Details
Published in:	Andrologia
Main Author:	Almabhouh F.A.; Singh H.J.
Format:	Article
Language:	English
Published:	Blackwell Publishing Ltd 2018
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018867577&doi=10.1111%2fand.12814&partnerID=40&md5=a37d67224b9b57b57fe977c24998b282

Similar Items

LY294002, a PI3K pathway inhibitor, prevents leptin-induced adverse effects on spermatozoa in Sprague-Dawley rats
by: Md Mokhtar A.H.; Malik I.A.; Abd Aziz N.A.A.; Almabhouh F.A.; Durairajanayagam D.; Singh H.J.
Published: (2019)

Effects of Profortil® on Leptin-Induced Adverse Effects on Sperm Parameters in Sprague-Dawley Rats
by: Alam Malik I.; Durairajanayagam D.; Henkel R.; Singh H.J.
Published: (2024)

Effects of Profortil® on Leptin-Induced Adverse Effects on Sperm Parameters in Sprague-Dawley Rats
by: Malik, et al.
Published: (2024)

Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats
by: Singh H.J.; Saleh H.I.; Gupalo S.; Omar E.
Published: (2013)

Effects of leptin on sperm count and morphology in Sprague-Dawley rats and their reversibility following a 6-week recovery period
by: Almabhouh F.A.; Osman K.; Siti Fatimah I.; Sergey G.; Gnanou J.; Singh H.J.
Published: (2015)

ACE2 activation by xanthenone prevents leptin-induced increases in blood pressure and proteinuria during pregnancy in Sprague-Dawley rats
by: Ibrahim H.S.; Froemming G.R.A.; Omar E.; Singh H.J.
Published: (2014)

Tocotrienol-rich fraction supplementation prevents foetal loss in females mated with corticosterone-treated male Sprague–Dawley rats
by: Abd Aziz N.A.A.; Chatterjee A.; Chatterjee R.; Durairajanayagam D.
Published: (2019)

Wound healing properties in Sprague-Dawley rats of marine endophytic fungi extracts
by: Aqilah H.M.; Norhayati A.S.; Siti A.A.
Published: (2018)

Leptin and reproductive dysfunction in obese men
by: Almabhouh F.A.; Md Mokhtar A.H.; Malik I.A.; Aziz N.A.A.A.; Durairajanayagam D.; Singh H.J.
Published: (2020)

The Photocatalytic Effects of Modified Hydrothermal Nanotitania Extraction on the Skin and Behavior of Sprague-Dawley Rats
by: Harun A.M.; Awang H.; Noor N.F.M.; Makhatar N.M.; Yusoff M.E.; Affandi N.D.N.; Alam M.K.
Published: (2021)

Effects of Gelam and Acacia honey acute administration on some biochemical parameters of Sprague Dawley rats
by: Samat S.; Nor N.A.M.; Nor Hussein F.; Ismail W.I.W.
Published: (2014)

Azadirachta excelsa improves renal morphology and function in streptozotocin induced-diabetic sprague dawley rats
by: Azmi N.S.A.; Hashim N.; Samsulrizal N.; Noor N.S.; Zin M.
Published: (2020)

Behavioral assessment and blood oxidative status of aging sprague dawley rats through a longitudinal analysis
by: Achin N.A.; Kit T.J.; Ngah W.Z.W.; Makpol S.; Mazlan M.; Hamezah H.S.; Damanhuri H.A.
Published: (2018)

Effects of antenatal, postpartum and post-weaning melatonin supplementation on blood pressure and renal antioxidant enzyme activities in spontaneously hypertensive rats
by: Lee S.K.; Sirajudeen K.N.S.; Sundaram A.; Zakaria R.; Singh H.J.
Published: (2011)

Leptin increases blood pressure and markers of endothelial activation during pregnancy in rats
by: Ibrahim H.S.; Omar E.; Froemming G.R.A.; Singh H.J.
Published: (2013)

Leptin in reproduction and hypertension in pregnancy
by: Singh H.; Almabhouh F.A.; Alshaikhli H.S.I.; Hassan M.J.M.; Daud S.; Othman R.; Md Salleh M.F.R.R.
Published: (2024)

The physicochemical characteristics of gelam honey and its outcome on the female reproductive tissue of sprague–dawley rats: A preliminary study
by: Ismail N.H.; Osman K.; Zulkefli A.F.; Mokhtar M.H.; Ibrahim S.F.
Published: (2021)

Impact of gentamicin coadministration along with high fructose feeding on progression of renal failure and metabolic syndrome in sprague-dawley rats
by: Ibraheem Z.O.; Basir R.; Aljobory A.K.; Ibrahim O.E.; Alsumaidaee A.; Yam M.F.
Published: (2014)

Editorial: Leptin in Physiology and Disease
by: Hryciw D.H.; Singh H.J.
Published: (2022)

Exogenous leptin administration decreases sperm count and increases the fraction of abnormal sperm in adult rats
by: Haron M.N.; D'Souza U.J.A.; Jaafar H.; Zakaria R.; Singh H.J.
Published: (2010)

General Health of Pregnant Sprague-Dawley Rats and Neonates’ Small Intestine Morphology upon Maternal Bisphenol A Exposure: A Preliminary Study
by: Zulkifli S.; Nor N.S.M.; Kadir S.H.S.A.; Ranai N.M.; Kornain N.K.M.; Rasdi Z.; Zain W.N.I.W.M.; Rahman A.A.; Khan J.; Jalaludin M.Y.
Published: (2022)

Protective effect of palm vitamin E and α-tocopherol against gastric lesions induced by water immersion restraint stress in Sprague-Dawley rats
by: Ibrahim I.; Yusof K.; Mohd Ismail N.; Mohd Fahami N.
Published: (2008)

Safety evaluation of orally-administered methanol extract of Muntingia calabura Linn. leaves: A sub-chronic toxicity study in Sprague Dawley rats
by: Md Nasir N.L.; Kamsani N.E.; Mohtarrudin N.; Md Tohid S.F.; Zakaria Z.A.
Published: (2020)

Prenatal Bisphenol a Exposure and Postnatal Trans Fat Diet Alter Small Intestinal Morphology and Its Global DNA Methylation in Male Sprague-Dawley Rats, Leading to Obesity Development
by: Zulkifli S.; Mohd Nor N.S.; Sheikh Abdul Kadir S.H.; Mohd Ranai N.; Mohd Kornain N.K.; Wan Mohd Zain W.N.I.; Abdul Aziz M.
Published: (2022)

The visual aspect of modified hydrothermal nanotitania extraction on skin of Spraque Dawley rats
by: Harun A.M.; Ibrahim M.K.W.; Awang H.; Rahman M.A.A.; Fadil F.; Affandi N.D.N.; Makhatar N.M.; Yusoff M.E.; Noor N.F.M.
Published: (2024)

Maternal EGCG intervention mitigates chronic hypertension during pregnancy in spontaneously hypertensive rats without adverse effects on pregnancy outcomes
by: Shao, et al.
Published: (2024)

Maternal EGCG intervention mitigates chronic hypertension during pregnancy in spontaneously hypertensive rats without adverse effects on pregnancy outcomes
by: Shao Y.; Lee S.-K.; Chua A.-L.; Chew Y.-L.; Liew K.B.
Published: (2024)

Non-uniform decay in jumping exercise-induced bone gains following 12 and 24 weeks of cessation of exercise in rats
by: Ooi F.-K.; Singh R.; Singh H.J.; Umemura Y.; Nagasawa S.
Published: (2011)

SOCIAL HOUSING ALLOCATION IN SCOTLAND: THE ADVERSE SELECTION ISSUES
by: Mahamood N.M.; MacGregor B.; Schulz R.; Majid R.A.; Wan Rodi W.N.
Published: (2023)

Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms
by: Gupta S.K.; Kumar B.; Nag T.C.; Agrawal S.S.; Agrawal R.; Agrawal P.; Saxena R.; Srivastava S.
Published: (2011)

Effect of cross-fostering on renal anti-oxidant/oxidant status and development of hypertension in spontaneously hypertensive rats
by: Lee S.K.; Sirajudeen K.N.S.; Sundaram A.; Zakaria R.; Singh H.J.
Published: (2011)

Effects of Standardized Aqueous Ethanolic Extract of Leaves of Ficus Deltoidea var. Trengganuensis on Blood Pressure in Spontaneously Hypertensive Rats
by: Radjeni Z.; Aziz M.A.; Azis N.A.; Kamal M.S.A.; Singh H.J.
Published: (2024)

Burden of Giardia duodenalis Infection and Its Adverse Effects on Growth of Schoolchildren in Rural Malaysia
by: Al-Mekhlafi H.M.; Al-Maktari M.T.; Jani R.; Ahmed A.; Anuar T.S.; Moktar N.; Mahdy M.A.K.; Lim Y.A.L.; Mahmud R.; Surin J.
Published: (2013)

COVID-19 Vaccine Hesitancy and Self-reported Adverse Effects: A Narrative Review
by: Noh N.; Karuppannan M.
Published: (2023)

A retrospective analysis of spontaneous adverse drug reactions reports relating to paediatric patients
by: Rosli R.; Ming L.C.; Aziz N.A.; Manan M.M.
Published: (2016)

Adverse effects of wi-fi radiation on male reproductive system: A systematic review
by: Jaffar F.H.F.; Osman K.; Ismail N.H.; Chin K.-Y.; Ibrahim S.F.
Published: (2019)

Enhancing The CBTC System in Urban Rail Transit
by: Ngadiron Z.; Bachok S.; Kamaluddin N.A.
Published: (2024)

Navigating the Polypharmacy Landscape: A Bibliometric Analysis of Computational Approaches for Predicting Adverse Drug Reactions
by: Ghafari A.T.; Zakaria Y.; Jahidin A.H.; Nazari Q.A.; Majeed A.B.A.; Hasan M.H.
Published: (2023)

Mobile Medical Applications for Dosage Recommendation, Drug Adverse Reaction, and Drug Interaction: Review and Comparison
by: Apidi N.A.; Murugiah M.K.; Muthuveloo R.; Soh Y.C.; Caruso V.; Patel R.; Ming L.C.
Published: (2017)

Polycentricity in practice: Marine governance transitions in Southeast Asia
by: Fortnam M.; Evans L.; Amira Mas Ayu A.M.; Bastian L.; Chaigneau T.; Creencia L.; Goh H.C.; Gonzales B.; Madarcos K.; Maharja C.; Mohd Iqbal M.; Ngoc Le T.; Praptiwi R.A.; Sugardjito J.; Van Nguyen Q.; Wan Nur Syazana W.M.A.
Published: (2022)