Synthesis of alpha amylase inhibitors based on privileged indole scaffold

Twenty five derivatives of indole carbohydrazide (1–25) had been synthesized. These compounds were characterized using 1H NMR and EI-MS, and further evaluated for their α-amylase inhibitory potential. The analogs (1–25) showed varying degree of α-amylase inhibitory potential. ranging between 9.28 an...

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Bibliographic Details
Published in:Bioorganic Chemistry
Main Author: Noreen T.; Taha M.; Imran S.; Chigurupati S.; Rahim F.; Selvaraj M.; Ismail N.H.; Mohammad J.I.; Ullah H.; javid M.T.; Nawaz F.; Irshad M.; Ali M.
Format: Article
Language:English
Published: Academic Press Inc. 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018732634&doi=10.1016%2fj.bioorg.2017.04.010&partnerID=40&md5=c1e0613a6e04e30e2cf7fbb9284b98e3