Chemical profiling and biological properties of Neolitsea kedahense Gamble essential oils

Hydrodistillation of the fresh stem and leaf of Neolitsea kedahense Gamble, collected from Gunung Jerai, Malaysia followed by the GC-FID and GC-MS analysis revealed the detection of a total of 47 constituents of which 28 (86.4%) from the stem and 31 (96.4%) constituents from the leaf. δ-Cadinene (17...

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Bibliographic Details
Published in:Natural Product Research
Main Author: Jani N.A.; Sirat H.M.; Ahmad F.; Mohamad Ali N.A.; Jamil M.
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2017
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85013769308&doi=10.1080%2f14786419.2017.1294172&partnerID=40&md5=0236a8b4731ba44f4bba902679581ff4
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Summary:Hydrodistillation of the fresh stem and leaf of Neolitsea kedahense Gamble, collected from Gunung Jerai, Malaysia followed by the GC-FID and GC-MS analysis revealed the detection of a total of 47 constituents of which 28 (86.4%) from the stem and 31 (96.4%) constituents from the leaf. δ-Cadinene (17.4%), 1-epi-cubenol (11.8%), cyperotundone (9.0%), cis-cadin-4-en-7-ol (7.7%), τ-cadinol (7.1%) and α-cadinol (7.1%) were the principle constituents in the stem oil, whereas β-caryophyllene (18.9%), bicyclogermacrene (18.6%) and trans-muurola-4(14),5-diene (9.8%) were the major constituents in the leaf oil. Among the identified constituents, three constituents namely 7-epi-α-selinene, junenol and cis-cadin-4-en-7-ol have not been found previously from Neolitsea oils. The stem and leaf oils were screened for their α-glucosidase inhibitory and antibacterial activities. Both oils displayed potential α-glucosidase inhibitory activity, while the stem oil possessed weak antibacterial activity against Bacillus subtilis. © 2017 Informa UK Limited, trading as Taylor & Francis Group.
ISSN:14786419
DOI:10.1080/14786419.2017.1294172