Ursodeoxycholic acid upregulates ERK and Akt in the protection of cardiomyocytes against CoCl2
Ursodeoxycholic acid (UDCA) is used to treat liver diseases and demonstrates cardioprotective effects. Accumulation of the plasma membrane sphingolipid sphingomyelin in the heart can lead to atherosclerosis and coronary artery disease. Sphingomyelinases (SMases) break down sphingomyelin, producing c...
| Published in: | Genetics and Molecular Research |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Fundacao de Pesquisas Cientificas de Ribeirao Preto
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011771016&doi=10.4238%2fgmr.15028150&partnerID=40&md5=b7f8089ab48055aece2c84d849640044 |