Irritable bowel syndrome and inflammatory bowel disease overlap syndrome: Pieces of the puzzle are falling into place

Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiolo...

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Bibliographic Details
Published in:Intestinal Research
Main Author: Rani R.A.; Ali R.A.R.; Lee Y.Y.
Format: Review
Language:English
Published: Korean Association for the Study of Intestinal Diseases 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006062750&doi=10.5217%2fir.2016.14.4.297&partnerID=40&md5=e3ca476a5d5b6b16ec1e51ecc921c14d
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Summary:Irritable bowel syndrome (IBS), a common gastrointestinal disorder involving the gut-brain axis, and inflammatory bowel disease (IBD), a chronic relapsing inflammatory disorder, are both increasing in incidence and prevalence in Asia. Both have significant overlap in terms of symptoms, pathophysiology, and treatment, suggesting the possibility of IBS and IBD being a single disease entity albeit at opposite ends of the spectrum. We examined the similarities and differences in IBS and IBD, and offer new thoughts and approaches to the disease paradigm. © 2016. Korean Association for the Study of Intestinal Diseases. All rights reserved.
ISSN:15989100
DOI:10.5217/ir.2016.14.4.297