Open-label study of absorption and clearance of 1% voriconazole eye drops

Open-label study of absorption and clearance of 1% voriconazole eye drops

Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous humor samples were attained over the first 80 min, which were higher than in...

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Published in:Antimicrobial Agents and Chemotherapy
Main Author: Neoh C.F.; Leung L.; Chan E.; Al-Badriyeh D.; Fullinfaw R.O.; Jhanji V.; Vajpayee R.B.; Davies G.E.; Stewart K.; Kong D.C.M.
Format: Article
Language:English
Published: American Society for Microbiology 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994525872&doi=10.1128%2fAAC.00683-16&partnerID=40&md5=7f7824bbc078c43461e06862abdf1401
id 2-s2.0-84994525872
spelling 2-s2.0-84994525872
Neoh C.F.; Leung L.; Chan E.; Al-Badriyeh D.; Fullinfaw R.O.; Jhanji V.; Vajpayee R.B.; Davies G.E.; Stewart K.; Kong D.C.M.
Open-label study of absorption and clearance of 1% voriconazole eye drops
2016
Antimicrobial Agents and Chemotherapy
60
11
10.1128/AAC.00683-16
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994525872&doi=10.1128%2fAAC.00683-16&partnerID=40&md5=7f7824bbc078c43461e06862abdf1401
Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous humor samples were attained over the first 80 min, which were higher than in vitro MIC90 values for typical fungi that cause keratitis. Copyright © 2016, American Society for Microbiology. All Rights Reserved.
American Society for Microbiology
664804
English
Article
All Open Access; Bronze Open Access
author Neoh C.F.; Leung L.; Chan E.; Al-Badriyeh D.; Fullinfaw R.O.; Jhanji V.; Vajpayee R.B.; Davies G.E.; Stewart K.; Kong D.C.M.
spellingShingle Neoh C.F.; Leung L.; Chan E.; Al-Badriyeh D.; Fullinfaw R.O.; Jhanji V.; Vajpayee R.B.; Davies G.E.; Stewart K.; Kong D.C.M.
Open-label study of absorption and clearance of 1% voriconazole eye drops
author_facet Neoh C.F.; Leung L.; Chan E.; Al-Badriyeh D.; Fullinfaw R.O.; Jhanji V.; Vajpayee R.B.; Davies G.E.; Stewart K.; Kong D.C.M.
author_sort Neoh C.F.; Leung L.; Chan E.; Al-Badriyeh D.; Fullinfaw R.O.; Jhanji V.; Vajpayee R.B.; Davies G.E.; Stewart K.; Kong D.C.M.
title Open-label study of absorption and clearance of 1% voriconazole eye drops
title_short Open-label study of absorption and clearance of 1% voriconazole eye drops
title_full Open-label study of absorption and clearance of 1% voriconazole eye drops
title_fullStr Open-label study of absorption and clearance of 1% voriconazole eye drops
title_full_unstemmed Open-label study of absorption and clearance of 1% voriconazole eye drops
title_sort Open-label study of absorption and clearance of 1% voriconazole eye drops
publishDate 2016
container_title Antimicrobial Agents and Chemotherapy
container_volume 60
container_issue 11
doi_str_mv 10.1128/AAC.00683-16
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994525872&doi=10.1128%2fAAC.00683-16&partnerID=40&md5=7f7824bbc078c43461e06862abdf1401
description Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous humor samples were attained over the first 80 min, which were higher than in vitro MIC90 values for typical fungi that cause keratitis. Copyright © 2016, American Society for Microbiology. All Rights Reserved.
publisher American Society for Microbiology
issn 664804
language English
format Article
accesstype All Open Access; Bronze Open Access
record_format scopus
collection Scopus
_version_ 1812871801928155136

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