Detection of CYP2C19 genetic variants in Malaysian Orang Asli from massively parallel sequencing data

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Detection of CYP2C19 genetic variants in Malaysian Orang Asli from massively parallel sequencing data

The human cytochrome P450 (CYP) is a superfamily of enzymes that have been a focus in research for decades due to their prominent role in drug metabolism. CYP2C is one of the major subfamilies which metabolize more than 10% of all clinically used drugs. In the context of CYP2C19, several key genetic...

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Bibliographic Details
Published in:	PLoS ONE
Main Author:	Ang G.Y.; Yu C.Y.; Subramaniam V.; Khalid M.I.H.A.; Aziz T.A.T.A.; James R.J.; Ahmad A.; Rahman T.A.; Nor F.M.; Ismail A.I.; Isa K.M.; Salleh H.; Teh L.K.; Salleh M.Z.
Format:	Article
Language:	English
Published:	Public Library of Science 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994385640&doi=10.1371%2fjournal.pone.0164169&partnerID=40&md5=bb0d86499943264b766af557747187d2

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