Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies
The synthesis of novel indolopyrazoline derivatives (P1-P4 and Q1-Q4) has been characterized and evaluated as potential anti-Alzheimer agents through in vitro Acetylcholinesterase (AChE) inhibition and radical scavenging activity (antioxidant) studies. Specifically, Q3 shows AChE inhibition (IC50: 0...
| Published in: | Bioorganic Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Academic Press Inc.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988957420&doi=10.1016%2fj.bioorg.2016.05.002&partnerID=40&md5=888f8a3acf498f30dda9c78f34d76321 |