Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]

Two butanolides, subamolide D (1) and subamolide E (2), along with β-sitosterol (3), β-sitostenone (4), lupeol (5), taraxerol (6), and 24-methylenelanosta-7,9(11)-diene-3β,15α-diol (7) were isolated from the leaves of Beilschmiedia glabra. The structures of the isolated compounds were elucidated by...

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Published in:	Marmara Pharmaceutical Journal
Main Author:	Salleh W.M.N.H.W.; Ahmad F.; Khong H.Y.; Zulkifli R.M.
Format:	Article
Language:	English
Published:	Marmara University 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988556968&doi=10.12991%2fmpj.20162079371&partnerID=40&md5=d3b4e6639228cf09665992d03c804cda

id	2-s2.0-84988556968
spelling	2-s2.0-84988556968 Salleh W.M.N.H.W.; Ahmad F.; Khong H.Y.; Zulkifli R.M. Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri] 2016 Marmara Pharmaceutical Journal 20 3 10.12991/mpj.20162079371 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988556968&doi=10.12991%2fmpj.20162079371&partnerID=40&md5=d3b4e6639228cf09665992d03c804cda Two butanolides, subamolide D (1) and subamolide E (2), along with β-sitosterol (3), β-sitostenone (4), lupeol (5), taraxerol (6), and 24-methylenelanosta-7,9(11)-diene-3β,15α-diol (7) were isolated from the leaves of Beilschmiedia glabra. The structures of the isolated compounds were elucidated by extensive spectroscopic data analysis and comparison with respective literature data. The compounds were tested for DPPH• radical scavenging, antimicrobial, acetylcholinesterase and lipoxygenase inhibitory activities. Compounds 1 and 2 displayed the strongest lipoxygenase assay with an IC50 value of 5.1 and 5.5 μM, respectively. All compounds showed weak activity on DPPH• radical-scavenging, antimicrobial, and acetylcholinesterase inhibition assays. © Marmara University. All rights reserved. Marmara University 13090801 English Article
author	Salleh W.M.N.H.W.; Ahmad F.; Khong H.Y.; Zulkifli R.M.
spellingShingle	Salleh W.M.N.H.W.; Ahmad F.; Khong H.Y.; Zulkifli R.M. Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
author_facet	Salleh W.M.N.H.W.; Ahmad F.; Khong H.Y.; Zulkifli R.M.
author_sort	Salleh W.M.N.H.W.; Ahmad F.; Khong H.Y.; Zulkifli R.M.
title	Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
title_short	Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
title_full	Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
title_fullStr	Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
title_full_unstemmed	Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
title_sort	Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]
publishDate	2016
container_title	Marmara Pharmaceutical Journal
container_volume	20
container_issue	3
doi_str_mv	10.12991/mpj.20162079371
url	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988556968&doi=10.12991%2fmpj.20162079371&partnerID=40&md5=d3b4e6639228cf09665992d03c804cda
description	Two butanolides, subamolide D (1) and subamolide E (2), along with β-sitosterol (3), β-sitostenone (4), lupeol (5), taraxerol (6), and 24-methylenelanosta-7,9(11)-diene-3β,15α-diol (7) were isolated from the leaves of Beilschmiedia glabra. The structures of the isolated compounds were elucidated by extensive spectroscopic data analysis and comparison with respective literature data. The compounds were tested for DPPH• radical scavenging, antimicrobial, acetylcholinesterase and lipoxygenase inhibitory activities. Compounds 1 and 2 displayed the strongest lipoxygenase assay with an IC50 value of 5.1 and 5.5 μM, respectively. All compounds showed weak activity on DPPH• radical-scavenging, antimicrobial, and acetylcholinesterase inhibition assays. © Marmara University. All rights reserved.
publisher	Marmara University
issn	13090801
language	English
format	Article
accesstype
record_format	scopus
collection	Scopus
_version_	1823296162983051264

Chemical constituents and bioactivities from the leaves of Beilschmiedia glabra Kosterm (Lauraceae); [Beilschmiedia glabra yapraklarıından izole edilen kimyasal bileşenlerin biyolojik etkinleri]

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