Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance

While age-related insulin resistance and hyperinsulinemia are usually considered to be secondary to changes in muscle, the liver also plays a key role in whole-body insulin handling and its role in age-related changes in insulin homeostasis is largely unknown. Here, we show that patent pores called...

詳細記述

書誌詳細
出版年:Aging Cell
第一著者: Mohamad M.; Mitchell S.J.; Wu L.E.; White M.Y.; Cordwell S.J.; Mach J.; Solon-Biet S.M.; Boyer D.; Nines D.; Das A.; Catherine Li S.-Y.; Warren A.; Hilmer S.N.; Fraser R.; Sinclair D.A.; Simpson S.J.; de Cabo R.; Le Couteur D.G.; Cogger V.C.
フォーマット: 論文
言語:English
出版事項: Blackwell Publishing Ltd 2016
オンライン・アクセス:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84977636917&doi=10.1111%2facel.12481&partnerID=40&md5=b64ffcfebcd96359be9ec2ce8400a7e4