Pharmacological evaluation of nasal delivery of selegiline hydrochloride-loaded thiolated chitosan nanoparticles for the treatment of depression

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Pharmacological evaluation of nasal delivery of selegiline hydrochloride-loaded thiolated chitosan nanoparticles for the treatment of depression

The aim of the present study was to investigate the propensity of thiolated chitosan nanoparticles (TCNs) to enhance the nasal delivery of selegiline hydrochloride. TCNs were synthesized by the ionic gelation method. The particle size distribution (PDI), entrapment efficiency (EE), and zeta potentia...

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Bibliographic Details
Published in:	Artificial Cells, Nanomedicine and Biotechnology
Main Author:	Singh D.; Rashid M.; Hallan S.S.; Mehra N.K.; Prakash A.; Mishra N.
Format:	Article
Language:	English
Published:	Taylor and Francis Ltd. 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84969913328&doi=10.3109%2f21691401.2014.998824&partnerID=40&md5=968df77dacae2cf76c0ad6eedf1adad0

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