Modulation of LOX and COX pathways via inhibition of amyloidogenesis contributes to mitoprotection against β-amyloid oligomer-induced toxicity in an animal model of Alzheimer's disease in rats

Several lines of evidence indicate that beta amyloid (β-A) production, neurofibrillary tangles and neuroinflammation are interrelated in the pathogenesis of Alzheimer's disease (AD). AD is associated with enhanced β-A production and accumulation resulting in neuroinflammation probably via activ...

Full description

Bibliographic Details
Published in:Pharmacology Biochemistry and Behavior
Main Author: Kalra J.; Kumar P.; Majeed A.B.A.; Prakash A.
Format: Article
Language:English
Published: Elsevier Inc. 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84965065061&doi=10.1016%2fj.pbb.2016.04.002&partnerID=40&md5=02506dc081522fc5625a21031f30a6ff

Similar Items