Modulation of LOX and COX pathways via inhibition of amyloidogenesis contributes to mitoprotection against β-amyloid oligomer-induced toxicity in an animal model of Alzheimer's disease in rats
Several lines of evidence indicate that beta amyloid (β-A) production, neurofibrillary tangles and neuroinflammation are interrelated in the pathogenesis of Alzheimer's disease (AD). AD is associated with enhanced β-A production and accumulation resulting in neuroinflammation probably via activ...
| Published in: | Pharmacology Biochemistry and Behavior |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Inc.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84965065061&doi=10.1016%2fj.pbb.2016.04.002&partnerID=40&md5=02506dc081522fc5625a21031f30a6ff |