Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation

A series of new α,β-unsaturated carbonyl-based cyclohexanone derivatives was synthesized by simple condensation method and all compounds were characterized by using various spectroscopic techniques. New compounds were evaluated for their effects on acetylcholinesterase (AChE) and butyrylcholinestera...

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Bibliographic Details
Published in:Bioorganic and Medicinal Chemistry
Main Author: Zha G.-F.; Zhang C.-P.; Qin H.-L.; Jantan I.; Sher M.; Amjad M.W.; Hussain M.A.; Hussain Z.; Bukhari S.N.A.
Format: Article
Language:English
Published: Elsevier Ltd 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84964391107&doi=10.1016%2fj.bmc.2016.04.015&partnerID=40&md5=551024feea300aef0866f459b343a642