Gamma-tocotrienol acts as a BH3 mimetic to induce apoptosis in neuroblastoma SH-SY5Y cells
Bcl-2 family proteins are crucial regulators of apoptosis. Both pro- and antiapoptotic members exist, and overexpression of the latter facilitates evasion of apoptosis in many cancer types. Bcl-2 homology domain 3 (BH3) mimetics are small molecule inhibitors of antiapoptotic Bcl-2 family members, an...
| Published in: | Journal of Nutritional Biochemistry |
|---|---|
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier Inc.
2016
|
| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959318848&doi=10.1016%2fj.jnutbio.2015.12.019&partnerID=40&md5=419a7115d8556312cd5374ace4d6eada |