Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde

QR Code

Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde

Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds we...

Full description

Bibliographic Details
Published in:	Asian Journal of Chemistry
Main Author:	Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
Format:	Article
Language:	English
Published:	Chemical Publishing Co. 2016
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954126061&doi=10.14233%2fajchem.2016.19168&partnerID=40&md5=b087b7bde6d2a5b0d0c1c9993c1295a4

Similar Items

Development of bis-thiobarbiturates as successful urease inhibitors and their molecular modeling studies
by: Rahim F.; Ali M.; Ullah S.; Rashid U.; Ullah H.; Taha M.; Javed M.T.; Rehman W.; Khan A.A.; Abid O.U.R.; Bilal M.
Published: (2016)

Synthesis of benzimidazole derivatives and their antiglycation, antioxidant, antiurease and molecular docking study
by: Taha M.; Rahim F.; Adalath B.; Imran S.; Mohammed Khan K.; Adnan Ali shah S.; Uddin N.; Nawaz M.; Break M.K.B.; Magam S.M.; Alqarni S.
Published: (2024)

Synthesis of benzimidazole derivatives and their antiglycation, antioxidant, antiurease and molecular docking study
by: Taha, et al.
Published: (2024)

Synthesis, In Vitro Enzymatic Inhibition, and Molecular Modeling of Novel Piperazine-Based Bis-Schiff Base Derivatives as Promising Anti-urease Agents
by: Masood N.; Hussain R.; Khan S.; Rahim F.; Mumtaz S.; Taha M.; Ur Rahman Abid O.; Iqbal T.; Adnan Ali Shah S.; Omar Al Wesabi E.; Magam S.M.
Published: (2024)

Synthesis, In Vitro Enzymatic Inhibition, and Molecular Modeling of Novel Piperazine-Based Bis-Schiff Base Derivatives as Promising Anti-urease Agents
by: Masood, et al.
Published: (2024)

Synthesis, in vitro thymidine phosphorylase inhibitory activity and molecular docking study of novel pyridine-derived bis-oxadiazole bearing bis-schiff base derivatives
by: Hussain R.; Rehman W.; Rahim F.; Khan S.; Alanazi A.S.; Alanazi M.M.; Rasheed L.; Khan Y.; Adnan. Ali. Shah S.; Taha M.
Published: (2023)

Synthesis of novel bisindolylmethane Schiff bases and their antibacterial activity
by: Imran S.; Taha M.; Ismail N.H.; Khan K.M.; Naz F.; Hussain M.; Tauseef S.
Published: (2014)

Synthesis, in vitro alpha-glucosidase inhibitory potential of benzimidazole bearing bis-Schiff bases and their molecular docking study
by: Rahim F.; Zaman K.; Taha M.; Ullah H.; Ghufran M.; Wadood A.; Rehman W.; Uddin N.; Shah S.A.A.; Sajid M.; Nawaz F.; Khan K.M.
Published: (2020)

Hybrid benzothiazole analogs as antiurease agent: Synthesis and molecular docking studies
by: Taha M.; Ismail N.H.; Imran S.; Wadood A.; Rahim F.; Khan K.M.; Riaz M.
Published: (2016)

Synthesis, in vitro antiurease, in vivo antinematodal activity of quinoline analogs and their in-silico study
by: Zaman K.; Rahim F.; Taha M.; Sajid M.; Hayat S.; Nawaz M.; Salahuddin M.; Iqbal N.; Khan N.U.; Shah S.A.A.; Farooq R.K.; Bahadar A.; Wadood A.; Khan K.M.
Published: (2021)

Synthesis, in vitro biological screening and docking study of benzo[d]oxazole bis Schiff base derivatives as a potent anti-Alzheimer agent
by: Taha M.; Rahim F.; Zaman K.; Anouar E.H.; Uddin N.; Nawaz F.; Sajid M.; Khan K.M.; Shah A.A.; Wadood A.; Rehman A.U.; Alhibshi A.H.
Published: (2023)

Synthesis of symmetrical bis-Schiff base-disulfide hybrids as highly effective anti-leishmanial agents
by: Taha M.; Sain A.A.; Ali M.; Anouar E.H.; Rahim F.; Ismail N.H.; Adenan M.I.; Imran S.; Al-Harrasi A.; Nawaz F.; Iqbal N.; Khan K.M.
Published: (2020)

Isatin based Schiff bases as inhibitors of α-glucosidase: Synthesis, characterization, in vitro evaluation and molecular docking studies
by: Rahim F.; Malik F.; Ullah H.; Wadood A.; Khan F.; Javid M.T.; Taha M.; Rehman W.; Ur Rehman A.; Khan K.M.
Published: (2015)

Anti-cancer potential of benzophenone-bis-Schiff bases on human pancreatic cancer cell line
by: Khan K.M.; Rasheed H.; Fatima B.; Hayat M.; Rahim F.; Ullah H.; Hameed A.; Taha M.; Tahir A.; Perveen S.
Published: (2016)

Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives
by: Kumar S.; Lim S.M.; Ramasamy K.; Vasudevan M.; Shah S.A.A.; Selvaraj M.; Narasimhan B.
Published: (2017)

Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases
by: Rahim F.; Ullah H.; Taha M.; Wadood A.; Javed M.T.; Rehman W.; Nawaz M.; Ashraf M.; Ali M.; Sajid M.; Ali F.; Khan M.N.; Khan K.M.
Published: (2016)

Antioxidant properties of phenolic Schiff bases: Structure-activity relationship and mechanism of action
by: Anouar E.H.; Raweh S.; Bayach I.; Taha M.; Baharudin M.S.; Di Meo F.; Hasan M.H.; Adam A.; Ismail N.H.; Weber J.-F.F.; Trouillas P.
Published: (2013)

Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors
by: Shah T.A.; Alam A.; Zainab; Khan M.; Elhenawy A.A.; Ayaz M.; Ali M.; Latif A.; Shah S.A.A.; Ahmad M.
Published: (2025)

Synthesis of Benzofuran–based Schiff bases as anti-diabetic compounds and their molecular docking studies
by: Adalat B.; Rahim F.; Taha M.; Hayat S.; Iqbal N.; Ali Z.; Shah S.A.A.; Wadood A.; Rehman A.U.; Khan K.M.
Published: (2022)

Synthesis and Molecular Docking of New Bis-Thiazolidinone-Based Chalcone Analogs as Effective Inhibitors of Acetylcholinesterase and Butyrylcholinesterase
by: Hussain R.; Rahim F.; Rehman W.; Taha M.; Khan S.; Zaman K.; Adnan Ali Shah S.; Wadood A.; Imran S.; Abdellatif M.H.
Published: (2022)

Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach
by: Gul, et al.
Published: (2024)

Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach
by: Gul S.; Alam A.; Zainab; Assad M.; Elhenawy A.A.; Islam M.S.; Shah S.A.A.; Parveen Z.; Shah T.A.; Ahmad M.
Published: (2024)

Acylhydrazide schiff bases: Synthesis and antiglycation activity
by: Khan K.M.; Taha M.; Rahim F.; Fakhri M.I.; Jamil W.; Khan M.; Rasheed S.; Karim A.; Perveen S.; Choudhary M.I.
Published: (2013)

Synthesis of Bis-indolylmethane sulfonohydrazides derivatives as potent α-Glucosidase inhibitors
by: Gollapalli M.; Taha M.; Ullah H.; Nawaz M.; AlMuqarrabun L.M.R.; Rahim F.; Qureshi F.; Mosaddik A.; Ahmat N.; Khan K.M.
Published: (2018)

Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase
by: Taha M.; Rashid U.; Imran S.; Ali M.
Published: (2018)

Synthesis of bis-indolylmethanes as new potential inhibitors of β-glucuronidase and their molecular docking studies
by: Taha M.; Ullah H.; Al Muqarrabun L.M.R.; Khan M.N.; Rahim F.; Ahmat N.; Ali M.; Perveen S.
Published: (2018)

Bis(indolyl)methanes synthesis through sodium iodate and sodium hydrogen sulfite in water
by: Khan K.M.; Rahim F.; Shah S.A.A.; Taha M.; Ismail N.H.; Manzoor M.; Miana G.A.; Perveen S.
Published: (2015)

Synthesis and biological evaluation of substituted benzohydrazide Schiff base adduct as potential cholinesterase inhibitors
by: Zulfiqar A.; Khan I.U.; Nabi M.; Ullah H.; Iqbal N.; Zeb B.; Hussain A.; Khan D.; Rab A.; Junaid S.M.; Taha M.; Shah S.A.A.; Rahim F.
Published: (2024)

Synthesis of modified Schiff base appended 1,2,4-triazole hybrids scaffolds: Elucidating the in vitro and in silico α-amylase and α-glucosidase inhibitors potential
by: Abbasi S.A.; Rahim F.; Hussain R.; Rehman W.; Khan S.; Taha M.; Iqbal T.; Khan Y.; Ali Shah S.A.
Published: (2024)

Synthesis of modified Schiff base appended 1,2,4-triazole hybrids scaffolds: elucidating the in vitro and in silico α-amylase and α-glucosidase inhibitors potential
by: Abbasi, et al.
Published: (2024)

Synthesis, anti-diabetic and in silico QSAR analysis of flavone hydrazide Schiff base derivatives
by: Jamil W.; Shaikh J.; Yousuf M.; Taha M.; Khan K.M.; Shah S.A.A.
Published: (2022)

Discovery of imidazopyridine derived oxadiazole-based thiourea derivatives as potential anti-diabetic agents: Synthesis, in vitro antioxidant screening and in silico molecular modeling approaches
by: Hussain R.; Rehman W.; Rahim F.; Khan S.; Taha M.; Khan Y.; Sardar A.; Khan I.; Shah S.A.A.
Published: (2023)

Synthesis and biological evaluation of substituted benzohydrazide Schiff base adduct as potential cholinesterase inhibitors
by: Zulfiqar, et al.
Published: (2024)

In vitro antioxidant and in silico enzyme inhibition studies of Carissa carandas Linn.: potential ingredient for nutraceutical development
by: Zubair M.; Tousif M.I.; Riaz N.; Saleem M.; Nazir M.; Tauseef S.; Hassan A.; Shah S.A.A.; Zengin G.; Hashem A.; Kumar A.; Abd_Allah E.F.
Published: (2024)

Crystal structure of 2,2'-(((2,2-dimethylpropane-1,3-diyl)bis(azanylylidene))- bis(methanylylidene))bis(4-methoxyphenol)palladium(II)
by: Ahmad S.N.; Bahron H.; Tajuddin A.M.; Sukeri M.M.Y.
Published: (2017)

Bis-pyrimidine acetamides: Design, synthesis and biological evaluation
by: Kumar S.; Lim S.M.; Ramasamy K.; Vasudevan M.; Shah S.A.A.; Narasimhan B.
Published: (2017)

Aryl-oxadiazole Schiff bases: Synthesis, α-glucosidase in vitro inhibitory activity and their in silico studies
by: Ullah H.; Rahim F.; Taha M.; Hussain R.; Tabassum N.; Wadood A.; Nawaz M.; Mosaddik A.; Imran S.; Wahab Z.; Miana G.A.; Kanwal; Khan K.M.
Published: (2020)

Secondary metabolite profiling, antioxidant capacity, enzyme inhibitory potential and in silico studies of Launaea intybacea (Jacq.) Beauverd: A multifunctional approach to probe into the new nutraceuticals
by: Qurat-ul-Ain; Saleem M.; Nazir M.; Riaz N.; Tousif M.I.; Tauseef S.; Hassan L.; Zengin G.; Sharifi-Rad M.; Shah S.A.A.
Published: (2023)

Discovering the DPPH Free Radical Scavenging Activity of Azine Derivatives Bearing Ethyl Phenyl Ketone Moiety
by: Rehman, et al.
Published: (2024)

Synthesis, biological evaluation and molecular docking study of indazole based schiff base analogues as new anti-diabetic inhibitors
by: Taha, et al.
Published: (2024)