Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde

Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde

Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds we...

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Published in:Asian Journal of Chemistry
Main Author: Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
Format: Article
Language:English
Published: Chemical Publishing Co. 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954126061&doi=10.14233%2fajchem.2016.19168&partnerID=40&md5=b087b7bde6d2a5b0d0c1c9993c1295a4
id 2-s2.0-84954126061
spelling 2-s2.0-84954126061
Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
2016
Asian Journal of Chemistry
28
1
10.14233/ajchem.2016.19168
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954126061&doi=10.14233%2fajchem.2016.19168&partnerID=40&md5=b087b7bde6d2a5b0d0c1c9993c1295a4
Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds were characterized by EI-MS and 1H NMR. All analogs were tested against antioxidant and urease inhibition. Few compounds were found to showed potent antiurease and antioxidant potential.
Chemical Publishing Co.
9707077
English
Article
All Open Access; Hybrid Gold Open Access
author Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
spellingShingle Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
author_facet Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
author_sort Rahim F.; Waseeq-Ur-Rehamn; Shehzad M.; Khan A.; Taha M.; Abid O.U.R.; Quereshi M.T.; Tauseef I.; Rehman W.
title Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
title_short Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
title_full Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
title_fullStr Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
title_full_unstemmed Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
title_sort Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
publishDate 2016
container_title Asian Journal of Chemistry
container_volume 28
container_issue 1
doi_str_mv 10.14233/ajchem.2016.19168
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954126061&doi=10.14233%2fajchem.2016.19168&partnerID=40&md5=b087b7bde6d2a5b0d0c1c9993c1295a4
description Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds were characterized by EI-MS and 1H NMR. All analogs were tested against antioxidant and urease inhibition. Few compounds were found to showed potent antiurease and antioxidant potential.
publisher Chemical Publishing Co.
issn 9707077
language English
format Article
accesstype All Open Access; Hybrid Gold Open Access
record_format scopus
collection Scopus
_version_ 1809678486373138432

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