Synthesis and antiurease & antioxidant activities of bis-Schiff bases of isophthalaldehyde
Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds we...
| Published in: | Asian Journal of Chemistry |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Chemical Publishing Co.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84954126061&doi=10.14233%2fajchem.2016.19168&partnerID=40&md5=b087b7bde6d2a5b0d0c1c9993c1295a4 |
| Summary: | Bis-Schiff bases of iosophthalaldehyde were synthesized by reacting isophthalaldehyde with hydrazine hydrate in 1:2 ratio in ethanol for 2-3 h under reflux. Product of first step was again reacted in 1:2 ratio with different aldehyde or acetophenone yielding bis-Schiff bases (1-16). All compounds were characterized by EI-MS and 1H NMR. All analogs were tested against antioxidant and urease inhibition. Few compounds were found to showed potent antiurease and antioxidant potential. |
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| ISSN: | 9707077 |
| DOI: | 10.14233/ajchem.2016.19168 |