A review of bisindolylmethane as an important scaffold for drug discovery
Bisindolylmethane and its derivatives are pharmacologically active and applicable in the field of pharmaceutical chemistry. Bisindolylmethanes have a variety of biological activities such as antihyperglycemic, antiinflammatory, antibacterial, anticancer, and antileishmanial activities, including enz...
| Published in: | Current Medicinal Chemistry |
|---|---|
| Main Author: | |
| Format: | Review |
| Language: | English |
| Published: |
Bentham Science Publishers B.V.
2015
|
| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953775700&doi=10.2174%2f0929867322666151006093930&partnerID=40&md5=80e6bb20323c8310294094c4bfcddbae |
| id |
2-s2.0-84953775700 |
|---|---|
| spelling |
2-s2.0-84953775700 Imran S.; Taha M.; Ismail N.H. A review of bisindolylmethane as an important scaffold for drug discovery 2015 Current Medicinal Chemistry 22 38 10.2174/0929867322666151006093930 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953775700&doi=10.2174%2f0929867322666151006093930&partnerID=40&md5=80e6bb20323c8310294094c4bfcddbae Bisindolylmethane and its derivatives are pharmacologically active and applicable in the field of pharmaceutical chemistry. Bisindolylmethanes have a variety of biological activities such as antihyperglycemic, antiinflammatory, antibacterial, anticancer, and antileishmanial activities, including enzyme inhibition activity. They play a crucial role in many diseases especially anticancer activity. Modifying their structure had proven to be useful in the search of new therapeutic agents. Extensive research carried out on bisindolylmethane and its derivatives shows that they are pharmacologically significant. The present review focuses on the pharmacological profile of bisindolylmethane derivatives. This review includes the current literature with an update of research findings as well as the perspectives that they hold for future research. © 2015 Bentham Science Publishers. Bentham Science Publishers B.V. 09298673 English Review |
| author |
Imran S.; Taha M.; Ismail N.H. |
| spellingShingle |
Imran S.; Taha M.; Ismail N.H. A review of bisindolylmethane as an important scaffold for drug discovery |
| author_facet |
Imran S.; Taha M.; Ismail N.H. |
| author_sort |
Imran S.; Taha M.; Ismail N.H. |
| title |
A review of bisindolylmethane as an important scaffold for drug discovery |
| title_short |
A review of bisindolylmethane as an important scaffold for drug discovery |
| title_full |
A review of bisindolylmethane as an important scaffold for drug discovery |
| title_fullStr |
A review of bisindolylmethane as an important scaffold for drug discovery |
| title_full_unstemmed |
A review of bisindolylmethane as an important scaffold for drug discovery |
| title_sort |
A review of bisindolylmethane as an important scaffold for drug discovery |
| publishDate |
2015 |
| container_title |
Current Medicinal Chemistry |
| container_volume |
22 |
| container_issue |
38 |
| doi_str_mv |
10.2174/0929867322666151006093930 |
| url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84953775700&doi=10.2174%2f0929867322666151006093930&partnerID=40&md5=80e6bb20323c8310294094c4bfcddbae |
| description |
Bisindolylmethane and its derivatives are pharmacologically active and applicable in the field of pharmaceutical chemistry. Bisindolylmethanes have a variety of biological activities such as antihyperglycemic, antiinflammatory, antibacterial, anticancer, and antileishmanial activities, including enzyme inhibition activity. They play a crucial role in many diseases especially anticancer activity. Modifying their structure had proven to be useful in the search of new therapeutic agents. Extensive research carried out on bisindolylmethane and its derivatives shows that they are pharmacologically significant. The present review focuses on the pharmacological profile of bisindolylmethane derivatives. This review includes the current literature with an update of research findings as well as the perspectives that they hold for future research. © 2015 Bentham Science Publishers. |
| publisher |
Bentham Science Publishers B.V. |
| issn |
09298673 |
| language |
English |
| format |
Review |
| accesstype |
|
| record_format |
scopus |
| collection |
Scopus |
| _version_ |
1814778509816496128 |