A new coumarin from stem bark of Mesua hexapetala
A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (...
| Published in: | Natural Product Research |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Taylor and Francis Ltd.
2016
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| Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951871945&doi=10.1080%2f14786419.2015.1120727&partnerID=40&md5=8f82a8bb7c4578e798a29054a860d1a6 |
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2-s2.0-84951871945 |
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| spelling |
2-s2.0-84951871945 Karunakaran T.; Ee G.C.L.; Teh S.S.; Daud S.; Mah S.H.; Lim C.K.; Jong V.Y.M.; Awang K. A new coumarin from stem bark of Mesua hexapetala 2016 Natural Product Research 30 14 10.1080/14786419.2015.1120727 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951871945&doi=10.1080%2f14786419.2015.1120727&partnerID=40&md5=8f82a8bb7c4578e798a29054a860d1a6 A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (8) were isolated from the stem bark of Mesua hexapetala (Clusiaceae), a plant, native to Malaysia. The structures of these compounds were elucidated and determined using spectroscopic techniques such as NMR and MS. Anti-inflammatory activity assay indicated hexapetarin (1) to possess moderate anti-inflammatory activity, while 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4) gave very good activity. © 2015 Taylor & Francis. Taylor and Francis Ltd. 14786419 English Article |
| author |
Karunakaran T.; Ee G.C.L.; Teh S.S.; Daud S.; Mah S.H.; Lim C.K.; Jong V.Y.M.; Awang K. |
| spellingShingle |
Karunakaran T.; Ee G.C.L.; Teh S.S.; Daud S.; Mah S.H.; Lim C.K.; Jong V.Y.M.; Awang K. A new coumarin from stem bark of Mesua hexapetala |
| author_facet |
Karunakaran T.; Ee G.C.L.; Teh S.S.; Daud S.; Mah S.H.; Lim C.K.; Jong V.Y.M.; Awang K. |
| author_sort |
Karunakaran T.; Ee G.C.L.; Teh S.S.; Daud S.; Mah S.H.; Lim C.K.; Jong V.Y.M.; Awang K. |
| title |
A new coumarin from stem bark of Mesua hexapetala |
| title_short |
A new coumarin from stem bark of Mesua hexapetala |
| title_full |
A new coumarin from stem bark of Mesua hexapetala |
| title_fullStr |
A new coumarin from stem bark of Mesua hexapetala |
| title_full_unstemmed |
A new coumarin from stem bark of Mesua hexapetala |
| title_sort |
A new coumarin from stem bark of Mesua hexapetala |
| publishDate |
2016 |
| container_title |
Natural Product Research |
| container_volume |
30 |
| container_issue |
14 |
| doi_str_mv |
10.1080/14786419.2015.1120727 |
| url |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951871945&doi=10.1080%2f14786419.2015.1120727&partnerID=40&md5=8f82a8bb7c4578e798a29054a860d1a6 |
| description |
A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (8) were isolated from the stem bark of Mesua hexapetala (Clusiaceae), a plant, native to Malaysia. The structures of these compounds were elucidated and determined using spectroscopic techniques such as NMR and MS. Anti-inflammatory activity assay indicated hexapetarin (1) to possess moderate anti-inflammatory activity, while 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4) gave very good activity. © 2015 Taylor & Francis. |
| publisher |
Taylor and Francis Ltd. |
| issn |
14786419 |
| language |
English |
| format |
Article |
| accesstype |
|
| record_format |
scopus |
| collection |
Scopus |
| _version_ |
1809678161319821312 |