Alteration in apyrase enzyme attenuated virulence of Shigella flexneri
Virulence of Shigella is attributed to the genes presence in chromosome or in the megaplasmid. The apy gene which is located in the megaplasmid of Shigella species encodes for apyrase enzyme, a pathogenesis-associated enzyme causing mitochondrial damage and host cell death. In this study we construc...
Published in: | Microbial Pathogenesis |
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Main Author: | |
Format: | Article |
Language: | English |
Published: |
Academic Press
2016
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Online Access: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951262933&doi=10.1016%2fj.micpath.2015.12.004&partnerID=40&md5=331b05b7b323ffb0ca600f5f281d001d |