Alteration in apyrase enzyme attenuated virulence of Shigella flexneri

Virulence of Shigella is attributed to the genes presence in chromosome or in the megaplasmid. The apy gene which is located in the megaplasmid of Shigella species encodes for apyrase enzyme, a pathogenesis-associated enzyme causing mitochondrial damage and host cell death. In this study we construc...

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Bibliographic Details
Published in:Microbial Pathogenesis
Main Author: BangaSingh K.K.; Nisha M.; Lau H.Y.; Ravichandran M.; Salleh M.Z.
Format: Article
Language:English
Published: Academic Press 2016
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951262933&doi=10.1016%2fj.micpath.2015.12.004&partnerID=40&md5=331b05b7b323ffb0ca600f5f281d001d