Composition of overlapping protein-protein and protein-ligand interfaces

Protein-protein interactions (PPIs) play a major role in many biological processes and they represent an important class of targets for therapeutic intervention. However, targeting PPIs is challenging because often no convenient natural substrates are available as starting point for small-molecule d...

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Bibliographic Details
Published in:PLoS ONE
Main Author: Mohamed R.; Degac J.; Helms V.
Format: Article
Language:English
Published: Public Library of Science 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84951058673&doi=10.1371%2fjournal.pone.0140965&partnerID=40&md5=463f13dd2ce87ea8b8e07a5a9a47a250