Antioxidant and α-glucosidase inhibitory constituents from Hornstedtia species of Malaysia

QR Code

Antioxidant and α-glucosidase inhibitory constituents from Hornstedtia species of Malaysia

Seven compounds were isolated from the n-hexane and chloroform extracts of the flowers and leaves of four Hornstedtia species and their structures were identified using spectroscopic techniques as 3,7,4′-trimethylkaempferol (1), 3,7-dimethylkaempferol (2), 7,4′-dimethylkaempferol (3), 3,5-dimethylka...

Full description

Bibliographic Details
Published in:	Natural Product Communications
Main Author:	Hashim S.E.; Sirat H.M.; Yen K.H.; Ismail I.S.; Matsuki S.N.
Format:	Article
Language:	English
Published:	Natural Product Incorporation 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84949997360&doi=10.1177%2f1934578x1501000919&partnerID=40&md5=87d8a1814164b169cffa71519bd1d682

Similar Items

Potentially bioactive metabolites from pineapple waste extracts and their antioxidant and α-glucosidase inhibitory activities by 1H NMR
by: Azizan A.; Lee A.X.; Hamid N.A.A.; Maulidiani M.; Mediani A.; Ghafar S.Z.A.; Zolkeflee N.K.Z.; Abas F.
Published: (2020)

Inhibitory Activity of Enzyme α-Glucosidase Ethanol Extract Combination of Mareme Plant (Glochidion arborescens (Müll. Arg.) Boerl.) and Leaves of the Sala Plant (Cynometra ramiflora Linn)
by: Haryoto; Arnida A.V.; Indrayudha P.; Muflihah C.H.; Yen K.H.
Published: (2023)

Evaluation of the enzyme inhibitory and antioxidant activities of entada spiralis stem bark and isolation of the active constituents
by: Roheem F.O.; Soad S.Z.M.; Ahmed Q.U.; Shah S.A.A.; Latip J.; Zakaria Z.A.
Published: (2019)

Biscoumarin analogs: Synthesis, α-glucosidase inhibitory potential and molecular docking study
by: Ahmat N.; Nik Abdullah Zawawi N.K.; Taha M.; Wadood A.; Rahim F.; Ullah H.
Published: (2020)

Chemical Constituents from Macaranga lowii King ex Hook.f. (Euphorbiaceae) and Their Effects on Antioxidant Activity
by: Kamarozaman A.S.; Nazeri H.M.; Ahmat N.; Zamkhuri Z.; Rajab N.F.; Ling S.E.; Azmin N.F.N.; Yusoff A.S.M.
Published: (2023)

Synthesis, α-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles
by: Taha M.; Ismail N.H.; Imran S.; Mohamad M.H.; Wadood A.; Rahim F.; Saad S.M.; Rehman A.U.; Khan K.M.
Published: (2016)

Synthesis, in vitro α-glucosidase inhibitory potential and molecular docking study of thiadiazole analogs
by: Javid M.T.; Rahim F.; Taha M.; Rehman H.U.; Nawaz M.; wadood A.; Imran S.; Uddin I.; Mosaddik A.; Khan K.M.
Published: (2018)

Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives
by: Khan K.M.; Qurban S.; Salar U.; Taha M.; Hussain S.; Perveen S.; Hameed A.; Ismail N.H.; Riaz M.; Wadood A.
Published: (2016)

Aryl-oxadiazole Schiff bases: Synthesis, α-glucosidase in vitro inhibitory activity and their in silico studies
by: Ullah H.; Rahim F.; Taha M.; Hussain R.; Tabassum N.; Wadood A.; Nawaz M.; Mosaddik A.; Imran S.; Wahab Z.; Miana G.A.; Kanwal; Khan K.M.
Published: (2020)

Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies
by: Salar U.; Taha M.; Khan K.M.; Ismail N.H.; Imran S.; Perveen S.; Gul S.; Wadood A.
Published: (2016)

A review on chemical constituents and biological activities of the genus beilschmiedia (Lauraceae)
by: Salleh W.M.N.H.W.; Ahmad F.; Yen K.H.; Zulkifli R.M.
Published: (2015)

Molecular Modeling and Synthesis of Indoline-2,3-dione-Based Benzene Sulfonamide Derivatives and Their Inhibitory Activity against α-Glucosidase and α-Amylase Enzymes
by: Rasheed L.; Rehman W.; Rahim F.; Ali Z.; Alanazi A.S.; Hussain R.; Khan I.; Alanazi M.M.; Naseer M.; Abdellattif M.H.; Hussain R.; Khan S.; Taha M.; Ali Shah S.A.
Published: (2023)

Hydrazinyl arylthiazole based pyridine scaffolds: Synthesis, structural characterization, in vitro α-glucosidase inhibitory activity, and in silico studies
by: Ali F.; Khan K.M.; Salar U.; Taha M.; Ismail N.H.; Wadood A.; Riaz M.; Perveen S.
Published: (2017)

α-Glucosidase inhibition of lactone intermediates of the iminosugar deoxynojirimycin
by: Haan Y.W.; Al-Bajalan H.M.; Sage E.E.; Elangovan D.; Yajit N.L.M.; Sarizan N.M.; Zitzmann N.; Kiappes J.L.; Hasbullah S.A.; Ismail N.H.; Mackeen M.M.
Published: (2019)

Molecular docking studies and in-vitro cholinesterase inhibitory activities of chemical constituents of Calophyllum gracilentum
by: Seruji N.M.U.; Jong V.Y.M.; Karunakaran T.; Zamakshshari N.H.; Mah S.H.; Gunter N.V.; Lizazman M.A.; Masayoshi A.
Published: (2024)

The Volatile Constituents from Lepidium sativum and Tridax procumbens Shoots Exhibit Antimicrobial Effect and Inhibitory Activities Against α-Amylase Enzyme and 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) Radical
by: Gafar M.K.; Okoye I.F.; Olatunji L.K.; Ahmad J.; Umar A.O.; Ibrahim O.S.; Salim F.; Ahmad R.
Published: (2024)

Antioxidant and anti-tyrosinase activities from Piper officinarum C.DC (Piperaceae)
by: Salleh W.M.N.H.W.; Ahmad F.; Yen K.H.
Published: (2014)

Exploring Acyl Thiotriazinoindole Based Pharmacophores: Design, Synthesis, and SAR Studies with Molecular Docking and Biological Activity Profiling against Urease, α-amylase, α-glucosidase, Antimicrobial, and Antioxidant Targets
by: Haider M.B.; Saeed A.; Ahmed A.; Azeem M.; Ismail H.; Mehmood S.; Taslimi P.; Shah S.A.A.; Irfan M.; El-Seedi H.R.
Published: (2024)

Synthesis, α-glucosidase inhibitory activity and in silico study of tris-indole hybrid scaffold with oxadiazole ring: As potential leads for the management of type-II diabetes mellitus
by: Taha M.; Rahim F.; Imran S.; Ismail N.H.; Ullah H.; Selvaraj M.; Javid M.T.; Salar U.; Ali M.; Khan K.M.
Published: (2017)

Exploring Acyl Thiotriazinoindole Based Pharmacophores: Design, Synthesis, and SAR Studies with Molecular Docking and Biological Activity Profiling against Urease, α-amylase, α-glucosidase, Antimicrobial, and Antioxidant Targets
by: Haider, et al.
Published: (2024)

Chemical Constituents from the Leaves and Stems of Piper ornatum N.E.Br (Piperaceae) and their Antioxidant Activity
by: Ainul Azman N.N.A.N.M.; Wan Salleh W.M.N.H.; Ghani N.A.; Rasol N.E.; Salihu A.S.
Published: (2024)

Synthesis of new oxadiazole derivatives as α-glucosidase inhibitors
by: Taha M.; Ismail N.H.; Imran S.; Rokei M.Q.B.; Saad S.M.; Khan K.M.
Published: (2015)

α-Glucosidase inhibition and docking studies of 5-deoxyflavonols and dihydroflavonols isolated from abutilon Pakistanicum
by: Hussain M.; Ahmed Z.; Khan S.N.; Shah S.A.A.; Razi R.; Imran S.; Khalid M.; Ali B.; Irshad M.B.; Nawaz F.; Chaudhry M.I.
Published: (2019)

Benzimidazole derivatives as new α-glucosidase inhibitors and in silico studies
by: Zawawi N.K.N.A.; Taha M.; Ahmat N.; Wadood A.; Ismail N.H.; Rahim F.; Azam S.S.; Abdullah N.
Published: (2016)

Synthesis and study of the α-amylase inhibitory potential of thiadiazole quinoline derivatives
by: Taha M.; Tariq Javid M.; Imran S.; Selvaraj M.; Chigurupati S.; Ullah H.; Rahim F.; Khan F.; Islam Mohammad J.; Mohammed Khan K.
Published: (2017)

ANTIOXIDANT POTENTIAL AND PHYTOCHEMICAL CONTENT FROM PEELS OF THREE DIFFERENT CITRUS SPECIES: A MINI REVIEW
by: Abdullah A.; Haron N.; Yusof H.; Camalxaman S.N.; Mohamed E.; Rambely A.S.
Published: (2023)

Synthesis, molecular docking studies of hybrid benzimidazole as α-glucosidase inhibitor
by: Zawawi N.K.N.A.; Taha M.; Ahmat N.; Ismail N.H.; Wadood A.; Rahim F.
Published: (2017)

Synthesis of Bis-indolylmethane sulfonohydrazides derivatives as potent α-Glucosidase inhibitors
by: Gollapalli M.; Taha M.; Ullah H.; Nawaz M.; AlMuqarrabun L.M.R.; Rahim F.; Qureshi F.; Mosaddik A.; Ahmat N.; Khan K.M.
Published: (2018)

Synthesis, α-amylase inhibitory potential and molecular docking study of indole derivatives
by: Taha M.; Baharudin M.S.; Ismail N.H.; Imran S.; Khan M.N.; Rahim F.; Selvaraj M.; Chigurupati S.; Nawaz M.; Qureshi F.; Vijayabalan S.
Published: (2018)

Oxindole based oxadiazole hybrid analogs: Novel α-glucosidase inhibitors
by: Taha M.; Imran S.; Rahim F.; Wadood A.; Khan K.M.
Published: (2018)

Correlation of chemical profiles obtained from 1H-NMR and LC–MS metabolomics with α-glucosidase inhibition activity for varietal selections of Ficus deltoidea
by: Kasim N.; Afzan A.; Mediani A.; Low K.H.; Ali A.M.; Mat N.; Wolfender J.-L.; Ismail N.H.
Published: (2022)

Synthesis of Indole Based Sulfonamide Derivatives as potent inhibitors of α-glucosidase and α-amylase in management of type-II diabetes
by: Ullah W.; Rahim F.; Hayat S.; Ullah H.; Taha M.; Khan S.; Khaliq A.; Bibi S.; Gohar O.; Iqbal N.; Shah S.A.A.; Khan K.M.
Published: (2024)

Synthesis, in vitro and Docking Studies of New Flavone Ethers as α-Glucosidase Inhibitors
by: Imran S.; Taha M.; Ismail N.H.; Kashif S.M.; Rahim F.; Jamil W.; Wahab H.; Khan K.M.
Published: (2016)

New thiazole-based thiazolidinone derivatives: Synthesis, in vitro α-amylase, α-glucosidase activities and silico molecular docking study
by: Khan S.; Ullah H.; Rahim F.; Taha M.; Hussain R.; Khan M.S.; Ali H.; Khan M.U.; Shah S.A.A.; Khan K.M.
Published: (2022)

In vitro evaluation of acetylcholinesterase inhibitory and neuroprotective activity in commiphora species: A comparative study
by: Dhivya P.S.; Selvamani P.; Latha S.; Mani V.; Azahan N.S.M.
Published: (2020)

Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives
by: Taha M.; Shah S.A.A.; Afifi M.; Imran S.; Sultan S.; Rahim F.; Khan K.M.
Published: (2018)

Chemical Constituents from Lindera subumbelliflora
by: Zaini N.N.M.; Salleh W.M.N.H.W.; Ghani N.A.; Rasol N.E.; Arzmi M.H.; Salihu A.S.; Khamis S.; Mahsop H.S.M.
Published: (2024)

Synthesis, biological activity and molecular docking of new tricyclic series as α-glucosidase inhibitors
by: Abuelizz H.A.; Iwana N.A.N.I.; Ahmad R.; Anouar E.-H.; Marzouk M.; Al-Salahi R.
Published: (2019)

Synthesis, in vitro α-glucosidase activity and in silico molecular docking study of isatin analogues
by: Ullah H.; Rahim F.; Ullah E.; Hayat S.; Zada H.; Khan F.; Wadood A.; Nawaz F.; Rehman Z.U.; Shah S.A.A.
Published: (2023)

Synthesis crystal structure of 2-methoxybenzoylhydrazones and evaluation of their α-glucosidase and urease inhibition potential
by: Taha M.; Ismail N.H.; Baharudin M.S.; Lalani S.; Mehboob S.; Khan K.M.; Yousuf S.; Siddiqui S.; Rahim F.; Choudhary M.I.
Published: (2015)