α-Glucosidase Activity Of Oleanolic Acid And Its Oxidative Metabolites: DFT and docking studies

A natural pentacyclic triterpenoid, oleanolic acid 1 and its biotransformed metabolites 2 and 3 are potential α-glucosidase inhibitors. To elucidate the inhibitory mechanism of compounds 1-3 against α-glucosidase, (i) their electronic and optical properties were calculated using DFT and TD-DFT metho...

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Bibliographic Details
Published in:Mini-Reviews in Medicinal Chemistry
Main Author: Anouar E.H.; Zakaria N.S.S.; Alsalme A.; Shah S.A.A.
Format: Article
Language:English
Published: Bentham Science Publishers 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84945947662&doi=10.2174%2f1389557515666150724154044&partnerID=40&md5=b35aecc81e2f62d4e9554ac99a6b1aa9

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