Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia

Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia

The epidemiology of non-typeable Haemophilus influenzae (NTHi) remains poorly understood. We therefore sought to determine the genetic relationship of 25 NTHi isolated from various states in Malaysia using multilocus sequence typing (MLST). The majority of isolates were obtained from sputum. There w...

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Published in:Infection, Genetics and Evolution
Main Author: Mohd-Zain Z.; Kamsani N.H.; Ahmad N.; Clarke S.C.
Format: Article
Language:English
Published: Elsevier B.V. 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943620835&doi=10.1016%2fj.meegid.2015.09.017&partnerID=40&md5=c11f450eaad95b96660a4420529d74db
id 2-s2.0-84943620835
spelling 2-s2.0-84943620835
Mohd-Zain Z.; Kamsani N.H.; Ahmad N.; Clarke S.C.
Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
2015
Infection, Genetics and Evolution
36

10.1016/j.meegid.2015.09.017
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943620835&doi=10.1016%2fj.meegid.2015.09.017&partnerID=40&md5=c11f450eaad95b96660a4420529d74db
The epidemiology of non-typeable Haemophilus influenzae (NTHi) remains poorly understood. We therefore sought to determine the genetic relationship of 25 NTHi isolated from various states in Malaysia using multilocus sequence typing (MLST). The majority of isolates were obtained from sputum. There were 24 novel sequence types (STs). Eight isolates were single-locus variants, the remainder being singletons. Clustering was not based on clinical site of isolation or geographical origin. Despite the limited number of isolates examined in this study, we demonstrate that NTHi isolates in Malaysia are diverse and warrant further investigation. © 2015 Elsevier B.V.
Elsevier B.V.
15671348
English
Article
All Open Access; Green Open Access
author Mohd-Zain Z.; Kamsani N.H.; Ahmad N.; Clarke S.C.
spellingShingle Mohd-Zain Z.; Kamsani N.H.; Ahmad N.; Clarke S.C.
Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
author_facet Mohd-Zain Z.; Kamsani N.H.; Ahmad N.; Clarke S.C.
author_sort Mohd-Zain Z.; Kamsani N.H.; Ahmad N.; Clarke S.C.
title Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
title_short Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
title_full Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
title_fullStr Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
title_full_unstemmed Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
title_sort Phylogenetic relationship of non-typeable Haemophilus influenzae isolated in Malaysia
publishDate 2015
container_title Infection, Genetics and Evolution
container_volume 36
container_issue
doi_str_mv 10.1016/j.meegid.2015.09.017
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84943620835&doi=10.1016%2fj.meegid.2015.09.017&partnerID=40&md5=c11f450eaad95b96660a4420529d74db
description The epidemiology of non-typeable Haemophilus influenzae (NTHi) remains poorly understood. We therefore sought to determine the genetic relationship of 25 NTHi isolated from various states in Malaysia using multilocus sequence typing (MLST). The majority of isolates were obtained from sputum. There were 24 novel sequence types (STs). Eight isolates were single-locus variants, the remainder being singletons. Clustering was not based on clinical site of isolation or geographical origin. Despite the limited number of isolates examined in this study, we demonstrate that NTHi isolates in Malaysia are diverse and warrant further investigation. © 2015 Elsevier B.V.
publisher Elsevier B.V.
issn 15671348
language English
format Article
accesstype All Open Access; Green Open Access
record_format scopus
collection Scopus
_version_ 1814778510098563072

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