Neuroprotective effect from stem bark extracts of Knema laurina against H2O2-and Aβ1-42-induced cell death in human SH-SY5Y cells

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Neuroprotective effect from stem bark extracts of Knema laurina against H2O2-and Aβ1-42-induced cell death in human SH-SY5Y cells

The stem bark extracts of Knema laurina inhibited the hydrogen peroxide (H2O2)-and aggregated amyloid β-peptide 1-42 length (Aβ1-42)-induced cell death in differentiated SH-SY5Y cells. Exposure of 250 μMH2O2 or 20 μM Aβ1-42 to the cells for 24 h reduced 50% of cell viability. Pretreatment of cells w...

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Bibliographic Details
Published in:	Natural Product Research
Main Author:	Ismail N.; Akhtar M.N.; Ismail M.; Zareen S.; Shah S.A.A.; Lajis N.H.; Tajuddin S.N.
Format:	Article
Language:	English
Published:	Taylor and Francis Ltd. 2015
Online Access:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84938959981&doi=10.1080%2f14786419.2014.985676&partnerID=40&md5=5f6250603f37b1e99488f7cf1966a24e

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