Synthesis of new oxadiazole derivatives as α-glucosidase inhibitors

Oxadiazole derivatives (6-28) having hydrazone linkage, were synthesized through condensation reaction between benzohydrazide 5 with various benzaldehydes. The oxadiazoles derivatives (6-28) were evaluated for their α-glucosidase inhibitory activity. The IC50 values for inhibition activity vary in t...

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Bibliographic Details
Published in:Bioorganic and Medicinal Chemistry
Main Author: Taha M.; Ismail N.H.; Imran S.; Rokei M.Q.B.; Saad S.M.; Khan K.M.
Format: Article
Language:English
Published: Elsevier Ltd 2015
Online Access:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937512790&doi=10.1016%2fj.bmc.2015.06.060&partnerID=40&md5=b85aea3cb0b6cb9f4e76c34887b78ffb